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REM Zone

product on market Capsule Ultimate Nutrition Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains melatonin, GABA, L-theanine, and 5-HTP, which are supported by moderate to strong evidence for promoting sleep and relaxation. These ingredients work by modulating neurotransmitters to reduce sleep latency and improve sleep quality. Research generally supports their efficacy for short-term use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for REM Zone
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

200 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
GABA
100 mg
2 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Gelatin Microcrystalline Cellulose Dicalcium Phosphate Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1 capsule 30-60 minutes before bedtime, or as recommended by a healthcare practitioner.

Warnings & Precautions

Warning: Do not use if under the age of 18. Keep out of reach of children

Do not use if pregnant or nursing. Consult a healthcare professional prior to use if you have any pre-existing medical conditions, or are taking prescription (including SSRI's) or over-the-counter medications or other supplements.

Do not use with other sleep medication. Improper use of this product will not improve results and is potentially hazardous to your health. Use only as directed. If you experience adverse effects, discontinue this product immediately and consult a healthcare professional. Do not drive or operate heavy machinery while using this product. Do not use if seal is broken or missing

Formulation Notes

Gluten-free!

Improve quality of sleep by up to 37% Improve morning alertness by up to 130% Increase relaxation in 40 minutes Increases REM sleep by almost 2 hours per night (53%)

Additional Information

Protect from heat, light, and moisture Store in a cool, dry place, 15-30 degrees C (59-86 degrees F) Dispose of container within 30 days of opening

Certified GMP Facility Inspected FDA Facility

Vitality series

Metadata

Product Details

UPC / SKU0 99071 87046 9
DSLD Entry Date2023-07-18
Product TypeOther Combinations
FormCapsule
DSLD ID293467
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.