🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Capsule(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

500 mg
📊 Market median: 200.0mg (107 products)
Median 200.0mg This product: 500mg
📊 Market median: 80.0mg (20 products) 📚 334 studies (Tier A: 8, B: 183)
This product: 60mg

Other Ingredients

Rice Dextrin Vegetable Cellulose Fructooligosaccharide Vegetable Magnesium Stearate Silica

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (82% of products) Nutrient (38% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Halal Gluten Free Dairy Free

Product Information

📋 Directions for Use

DIRECTIONS: For best results take 2 capsules per day before or during meals.

⚠️ Warnings & Precautions

CAUTION: ~ Do not take if seal is broken

~ Keep out of reach of children

~ As with any supplement, if you are pregnant, nursing, have a medical condition or taking medication, consult your health practitioner before use

🧪 Formulation Notes

PROBIOTICS with DDS-1

NON-DAIRY NON-GMO GLUTEN FREE SOY FREE PRESERVATIVE FREE

VEGAN

We start with exceptionally resilient, scientically validated strains like Lactobacillus acidophilus DDS(R)-1 as a base for all of our formulas.

Additional Information

5 BILLION CFU 1 MONTH SUPPLY ACID & BILE RESISTANT

SUPPORTS DIGESTIVE and IMMUNE HEALTH

~leading ~scientific ~healthy ~trusted UP4 learning more about the art, science and passion that goes into our products?

Laboratory tested to meet strict standards for potency and identity.

MADE IN USA

{crescent moon}M(R)

OK D

vitamin angels(R) PROUD SUPPORTER

Room temperature stable for two years. Refrigerate after opening.

UP4 health. Our formulas are based on the researched and proven strains that promote the healthy bacteria in your body. With probiotics and your body in balance, the results are a happier inside.

UP4 trust. We stand on our legacy of quality. We’re dedicated to being a leader in the field and guarantee you will always get what is promised on our label. It’s what you’d expect from a company that’s all in for probiotics.

UP4 leading. We’ve been making probiotics in the USA since 1979. And it’s all we do, from creating the formulas and manufacturing to getting our products to you. For us, it’s a science, an art and definitely our passion.

UP4 science. Not all probiotic strains are created equal.

We add additional live cultures that can naturally withstand stomach acid and bile without the need for chemical coatings.

Laboratory tested to meet strict standards for potency and purity. Potency guaranteed at time of expiration.

Product Details

DSLD Entry Date 2013-12-24
Product Type Non-Nutrient/Non-Botanical
Form Capsule
Brand UP4
DSLD ID 28840
Data Updated 2026-04-11

Research Evidence

10 Research Sources
51 Avg Quality Score
3 Meta Analysis
3 Rct
2 Systematic Review
2 Clinical Trial
B The effect of Spirulina supplementation on lipid profile: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials
Meta Analysis Pharmacological research 2023
B A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2016
B Potential benefits of microalgae intake against metabolic diseases: beyond spirulina-a systematic review of animal studies
Systematic Review Nutrition reviews 2024
C The effects of Spirulina supplementation on metabolic syndrome components, its liver manifestation and related inflammatory markers: A systematic review
Systematic Review Complementary therapies in medicine 2019
C The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytotherapy research : PTR 2019
C The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double-blind, controlled trial
Rct Phytotherapy research : PTR 2023
C Antioxidant Efficacy of a Spirulina Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome.
Rct Marine drugs
C Combined high-intensity interval training and spirulina supplementation synergistically improve inflammatory and lipid-associated biomarkers in men with obesity.
Rct Nutrition research (New York, N.Y.)
C The Effects of Spirulina Platensis on Insulin Resistance in HIV-infected Patients
Clinical Trial ClinicalTrials.gov 2008
C Carbon-13 (13C)-Spirulina Platensis Gastric Emptying Breath Test (GEBT)
Clinical Trial ClinicalTrials.gov 2010
View all evidence for Spirulina →

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