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Estrotone

product on market Capsule New Chapter Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 17% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This blend contains black cohosh and chaste tree berry, which have moderate evidence for managing menopausal symptoms. Evening primrose oil and schizandra are included for hormonal support, though clinical evidence for these specific extracts is more limited. Ginger is commonly used to support digestive health and reduce inflammation.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Estrotone
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Botanical
Product Type
17%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Evening Primrose Oil Supercritical Seed Extract
200 mg
Schizandra hydroethanolic extract
160 mg
50 mg
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)
Market median: 80.0mg (136 products)
Chaste Tree Berry Hydroethanolic Extract
40 mg
Rosemary Leaf Supercritical Extract
10 mg

Other Ingredients

extra-virgin Olive Oil Hypromellose Yellow Beeswax Candelilla Wax
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: One Capsule Daily With Food.

Warnings & Precautions

Not recommended for use in children.

Caution: Contact a healthcare professional prior to use if taking birth control, planning surgery, have a pre-existing liver disorder, history of cancer or pituitary disorders. Do not use if pregnant, nursing, considering pregnancy, or taking contraceptives.

Discontinue use and consult a healthcare professional if you develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice.

Keep out of reach of children.

Read ingredients carefully and avoid use if known sensitivity to any ingredient.

Formulation Notes

Certified Gluten-Free by NSF; 100% vegetarian; no artificial flavors or colors.

Certified Gluten-Free by NSF; 100% vegetarian; no artificial flavors or colors.

Chaste Tree Blend

Pure & Potent Extracts Herbal Hormonal Balance

Pre- & Post- Menopause

Non GMO

Manufactured in the US from Globally Sourced Ingredients

Additional Information

Please refer to newchapter.com for more information about this product and its benefits.

The New Chapter Money-Back Guarantee We proudly stand behind every product we make. However, if you are not satisfied, please visit www.newchapter.com/guarantee for refund details. Please Recycle This Bottle After Use.

Non GMO Project Verified nongmoproject.org NSF Certified Gluten-free Certified B Corporation

For questions or comments call 888-874-4461

Metadata

Product Details

DSLD Entry Date2023-06-22
Product TypeBotanical
FormCapsule
BrandNew Chapter
DSLD ID288194
Data Updated2026-04-11
Research

Research Evidence

31
Research Sources
49
Avg Quality
23
Systematic Review
5
Meta Analysis
1
Rct
1
Openfda Safety
B [Efficacy of black cohosh extracts for improving low estrogen status induced by postoperative GnRHa treatment in patients with endometriosis: a systematic review]
Systematic Review Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 2020 PubMed
B Black cohosh (Cimicifuga spp.) for menopausal symptoms
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
B Vasomotor symptoms resulting from natural menopause: a systematic review and network meta-analysis of treatment effects from the National Institute for Health and Care Excellence guideline on menopause
Systematic Review BJOG : an international journal of obstetrics and gynaecology 2017 PubMed DOI
C Suspected black cohosh hepatotoxicity: no evidence by meta-analysis of randomized controlled clinical trials for isopropanolic black cohosh extract
Meta Analysis Menopause (New York, N.Y.) 2011 PubMed DOI
C Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms - an update on the evidence
Meta Analysis Climacteric : the journal of the International Menopause Society 2021 PubMed DOI
C Menopausal symptoms
Systematic Review BMJ clinical evidence 2007 PubMed
C Menopausal symptoms
Systematic Review BMJ clinical evidence 2011 PubMed
C Menopausal symptoms
Systematic Review BMJ clinical evidence 2010 PubMed
C Black cohosh extracts in women with menopausal symptoms: an updated pairwise meta-analysis
Meta Analysis Menopause (New York, N.Y.) 2023 PubMed DOI
C Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis
Meta Analysis Alternative therapies in health and medicine 2010 PubMed
View all evidence for Black Cohosh →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.