🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1500mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 100mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 450mg

Other Ingredients

Cellulose Crospovidone Stearic Acid FD&C Yellow #5 Lake FD&C Yellow #6 Lake Guar Gum Magnesium Silicate Maltodextrin Medium Chain Triglyceride Polydextrose Silica Titanium Dioxide Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: For adults, take two (2) tablets daily preferably with a meal.

⚠️ Warnings & Precautions

WARNING: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Contains shellfish (crab, crayfish, lobster, shrimp) ingredients.

🧪 Formulation Notes

Made in the USA with select ingredients from around the world.

Antioxidant Power Individual Results May Vary

Glucosamine boswellia + Turmeric with 5-LOXIN ADVANCED

Shows Improvement in Joint Comfort Within 7 Days

Additional Information

Store at room temperature.

Based on two human studies with 5-LOXIN ADVANCED where subjects rated their joint health over time, subjects' joint health improved within 7 days, and continued to improve throughout the duration of the studies.

To reorder item # 25685 www.puritan.com 1-800-645-1030

QA Quality Assured

Refers to level of Glucosamine HCI per tablet compared to item number 44772.

Product Details

UPC / SKU 0 25077 00081 4
DSLD Entry Date 2023-05-24
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 285585
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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