🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
33 Servings
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

3 Gram(s)
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 3mg

Other Ingredients

Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Vegetarian Coating

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (82% of products) Nutrient (8% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested usage: Take 1-3 tablets twice daily, preferably with food.

⚠️ Warnings & Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

This product is very sensitive to moisture/humidity which may affect the product stability.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

Betaine Anhydrous, or TMG (Trimethylglycine) is known to facilitate methylation processes. Methylation is a normal biological process that is critical for DNA repair, liver detoxification mechanisms, lipid metabolism, and the production of SAMe. It is also an important step in the conversion of homocysteine, a damaging amino acid, into a friendlier amino acid, methionine. Supplementation with TMG has been shown in clinical and non-clinical studies to support healthy homocysteine levels already within normal range.

Supports healthy homocysteine levels Promotes normal methylation processes

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Produced in a GMP facility that processes other ingredients containing these allergens. Natural color variation may occur in this product.

V Vegan

Additional Information

Keep the bottle tightly closed at all times in between usage. Keep the freshness packet in bottle. This product is very sensitive to moisture/humidity which may affect the product stability. Store in a cool, dry place after opening.

1 year happiness guarantee

Guaranteed quality & potency

Please recycle.

Product Details

UPC / SKU 8 10026 42278 2
DSLD Entry Date 2023-03-22
Product Type Non-Nutrient/Non-Botanical
Form Tablet or Pill
Brand LuckyVitamin
DSLD ID 283306
Data Updated 2026-04-11

Research Evidence

23 Research Sources
47 Avg Quality Score
18 Rct
3 Systematic Review
1 Meta Analysis
1 Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009
View all evidence for Betaine →

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