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MSM Joint Formula

product on market Capsule Natural Factors Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine and chondroitin sulfate are commonly used to support joint structure, though research evidence for their efficacy is moderate and mixed. OptiMSM may help reduce joint pain and inflammation. Overall, clinical evidence for this specific combination of ingredients remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for MSM Joint Formula
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
90
Servings
Non-Nutrient/Non-Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Sodium
25 mg (1% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 1000.0mg (2 products)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Gelatin Water, Purified Magnesium Stearate Rice, Powder
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: 1 capsule 4-6 times per day or as directed by a health professional.

Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Contains shellfish (shrimp and crab).

Formulation Notes

MSM Joint Formula is a combination of well-known joint support ingredients that work together to maintain healthy joints. Glucosamine and chondroitin provide support for healthy cartilage while MSM supports the joints and muscles. Taken together, these three nutrients provide triple joint support.

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, corn, egg, fish, tree nuts, or GMOs.

With glucosamine & chondroitin sulfate

Helps maintain structural integrity of joints & connective tissue

Additional Information

ISURA Non-GMO Mass Spec Documentation Lab tested

For freshness, store in a cool, dry place.

Recyclable container and label.

Metadata

Product Details

UPC / SKU0 68958 02695 4
DSLD Entry Date2023-02-21
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID282400
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.