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Confidence

product on market Unknown Thesis Safety: 95/100
95/100

This product looks safe

  • Magnesium L-Threonate: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula utilizes ingredients like Zembrin and Affron, which have moderate evidence for supporting mood and stress response. Magnesium L-Threonate is included for cognitive support, though overall evidence coverage for this specific combination is limited. The profile maintains a high safety score with minimal reported concerns.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium L-Threonate: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Confidence
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Packet(s)
Serving Size
6
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Zembrin
25 mg
Dihydrohonokiol-B
10 mg
Affron
28 mg
Shoden
120 mg
Exceeds UL by 1.4× (UL: 350 mg) 316 studies (A:8, B:159)
333 mg
Market median: 500.0mg (82 products) 19 studies (A:1, B:6)
100 mg
Market median: 180.0mg (239 products) 49 studies (A:1, B:19)
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)

Other Ingredients

Magnesium Stearate Microcrystalline Cellulose Rice Flour Silicon Dioxide Stearic Acid
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Warnings & Precautions

Caution: Do not take more than 2 packets in a 24 hour period.

Do not use if you are pregnant, nursing or under the age of 18.

Do not use if you are pregnant, nursing or under the age of 18. Keep out of reach of children.

Warning: Consult your healthcare professional before use if you have a medical condition or are taking medication, specifically antidepressant or anxiety medication.

Discontinue use two weeks prior to surgery.

Formulation Notes

Formulated to: Promote peace of mind, no matter what the day has in store. Supports mood, soothes nerves, and prevents you from feeling overwhelmed.

Best for: High-pressure situations Expanding your comfort zone Taking a fist step

Metadata

Product Details

UPC / SKUTHS-000110
DSLD Entry Date2022-10-24
Product TypeOther Combinations
FormUnknown
BrandThesis
DSLD ID278272
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.