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Niacin

product on market Tablet or Pill Nature's Sunshine Safety: 70/100
70/100

Review before taking

  • Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Niacin is supported by strong evidence for managing lipid levels and supporting cardiovascular health. The proprietary blend lacks specific data, and overall evidence coverage for this formulation is limited. This product maintains a moderate safety profile.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product has a lower safety score because it contains an amount of Niacin that significantly exceeds the recommended daily upper limit. Additionally, it uses a proprietary blend, meaning the exact amounts of some ingredients are not disclosed.

Label

Product Label

Label for Niacin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Vitamin
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mg NE (1563% DV)
Exceeds UL by 7.1× (UL: 35 mg) 196 studies (A:5, B:63)
Proprietary Blend
10 mg

Other Ingredients

Dicalcium Phosphate Cellulose Stearic Acid Silicon Dioxide Vegetable Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Use: Take 1 tablet daily with a meal.

Warnings & Precautions

Pregnant or lactating women should consult their health care professional prior to taking this supplement.

Do not use if inner seal is missing or damaged.

Formulation Notes

Ko Pareve (Kosher)

Circulatory system support Support the nervous system

Guaranteed pure

Additional Information

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

We source the world's purest ingredients, no matter where they are grown, to ensure the active nutrients are delivered just as nature intended.

Ko Pareve (Kosher)

New look! Same great product

Metadata

Product Details

UPC / SKU0 99904 01797 9
DSLD Entry Date2022-10-24
Product TypeVitamin
FormTablet or Pill
DSLD ID278188
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.