🟡 60/100

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  • Nicotinamide: 1500mg is 42.9× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
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Safety Alerts

⚠️ Nicotinamide: 1500mg is 42.9× the Tolerable Upper Intake Level (35mg)

This product has a low safety score because the dose of nicotinamide is significantly higher than the recommended maximum daily limit.

Label Data

1 Tablet(s) Serving Size
60 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

1500 mg (9375% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 42.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 1500mg UL 35mg

Other Ingredients

Stearic Acid Hydroxypropyl Cellulose Silica Cellulose Gum Magnesium Stearate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested usage: As a dietary supplement take one tablet daily.

⚠️ Warnings & Precautions

Caution: For adults only.

If you are pregnant, may become pregnant, or breastfeeding, consult your healthcare professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

🧪 Formulation Notes

Nicotinamide is a water-soluble amide of nicotinic acid. It is an essential member of the B-vitamin family and it does not cause a niacin flush. Biophix Nicotinamide 1500 mg is the highest strength available, non-GMO, flush free and suitable for vegetarians. Nicotinamide and Niacin are two different forms of vitamin B-3.

Biophix Nicotinamide 1500 mg is the highest strength available, non-GMO, flush free and suitable for vegetarians.

Biophix Nicotinamide 1500 mg is the highest strength available, non-GMO, flush free and suitable for vegetarians.

Manufactured In A GMP Inspected Facility Made in USA

Maximum Strength Nicotinamide 1500 mg

Flush-free, tested, non-GMO High potency vitamin, gluten free

High potency vitamin, gluten free

Vegan

GMP Tested

Suitable for vegetarians and hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Suitable for vegetarians and hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Vegetarian/Vegan product.

Vegan

Gluten free GMO free

GMP tested

Additional Information

Manufactured In A GMP Inspected Facility Made in USA

Store in a cool, dry place.

Product Details

UPC / SKU X001N4JP31
DSLD Entry Date 2022-11-22
Product Type Vitamin
Form Tablet or Pill
Brand Biophix
DSLD ID 277943
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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