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Nicotinamide 1500 mg

product on market Tablet or Pill Biophix Safety: 60/100
60/100

Review before taking

  • Nicotinamide: 1500mg is 42.9× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Nicotinamide is a form of vitamin B3 used to support cellular energy metabolism and skin health, though evidence for high-dose supplementation is limited. Due to the high 1500 mg dosage, potential safety concerns regarding liver toxicity or gastrointestinal distress may exist. Consult a healthcare provider regarding this concentration.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide: 1500mg is 42.9× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 1,500mg of Nicotinamide, which is significantly higher than the recommended upper limit of 35mg.

Label

Product Label

Label for Nicotinamide 1500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1500 mg (9375% DV)
Exceeds UL by 42.9× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Stearic Acid Hydroxypropyl Cellulose Silica Cellulose Gum Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: As a dietary supplement take one tablet daily.

Warnings & Precautions

Caution: For adults only.

If you are pregnant, may become pregnant, or breastfeeding, consult your healthcare professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formulation Notes

Nicotinamide is a water-soluble amide of nicotinic acid. It is an essential member of the B-vitamin family and it does not cause a niacin flush. Biophix Nicotinamide 1500 mg is the highest strength available, non-GMO, flush free and suitable for vegetarians. Nicotinamide and Niacin are two different forms of vitamin B-3.

Biophix Nicotinamide 1500 mg is the highest strength available, non-GMO, flush free and suitable for vegetarians.

Biophix Nicotinamide 1500 mg is the highest strength available, non-GMO, flush free and suitable for vegetarians.

Manufactured In A GMP Inspected Facility Made in USA

Maximum Strength Nicotinamide 1500 mg

Flush-free, tested, non-GMO High potency vitamin, gluten free

High potency vitamin, gluten free

Vegan

GMP Tested

Suitable for vegetarians and hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Suitable for vegetarians and hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Vegetarian/Vegan product.

Vegan

Gluten free GMO free

GMP tested

Additional Information

Manufactured In A GMP Inspected Facility Made in USA

Store in a cool, dry place.

Metadata

Product Details

UPC / SKUX001N4JP31
DSLD Entry Date2022-11-22
Product TypeVitamin
FormTablet or Pill
BrandBiophix
DSLD ID277943
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.