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Joint Flex

product on market Capsule Priority One Nutritional Supplements Safety: 92/100
92/100

This product looks safe

  • Manganese: 24mg is 2.2× the Tolerable Upper Intake Level (11mg)
  • 60% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines glucosamine and chondroitin, which have moderate evidence for supporting joint health. Bromelain and frankincense are included for their researched anti-inflammatory properties, while manganese supports connective tissue. Overall, the evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Manganese: 24mg is 2.2× the Tolerable Upper Intake Level (11mg)

Label

Product Label

Label for Joint Flex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

24 mg (1043% DV)
Exceeds UL by 2.2× (UL: 11 mg) 9 studies — no high-quality reviews
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
20 mg
Market median: 200.0mg (136 products) 3 studies — no high-quality reviews
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)

Other Ingredients

Silicon Dioxide Maltodextrin Sodium Sulfate Capsule
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: Take two (2) capsules in the morning and two (2) capsules in the evening for the first 60 days, then adjust according to needs, or as directed by your physician.

Warnings & Precautions

Warning: If you are pregnant or breast feeding, consult your physician before using this product.

Some ingredients derived from shellfish.

Keep out of reach of children.

Contains crustacean shellfish (crayfish).

Formulation Notes

Contains no preservatives.

Non-GMO

Additional Information

Keep container tightly closed, store in a cool, dry place.

Bisphenol-A (BPA) & Phthalate Free

GMP Certified

For professional use only.

Metadata

Product Details

UPC / SKU8 15354 02077 8
DSLD Entry Date2022-11-22
Product TypeOther Combinations
FormCapsule
BrandPriority One Nutritional Supplements
DSLD ID277377
Data Updated2026-04-11
Research

Research Evidence

11
Research Sources
47
Avg Quality
7
Rct
2
Meta Analysis
1
Regulatory Source
C Trace elements and Alzheimer dementia in population-based studies: A bibliometric and meta-analysis
Meta Analysis Environmental pollution (Barking, Essex : 1987) 2023 PubMed DOI
C Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone
Rct Journal of animal science 2010 PubMed DOI
C Reducing mineral usage in feedlot diets for Nellore cattle: II. Impacts of calcium, phosphorus, copper, manganese, and zinc contents on intake, performance, and liver and bone status
Rct Journal of animal science 2017 PubMed DOI
C Copper, Ceruloplasmin, Zinc, and Manganese Levels in Brain and Biological Fluids from Parkinson's Disease Patients: Systematic Review and Meta-Analysis
Meta Analysis Cells 2026 PubMed DOI
C Risedronate reverses bone loss in postmenopausal women with low bone mass: results from a multinational, double-blind, placebo-controlled trial. BMD-MN Study Group
Rct The Journal of clinical endocrinology and metabolism 2000 PubMed
C Dietary Reference Intakes: Manganese
Regulatory Source IOM/NAM Dietary Reference Intakes 2000
C Vitamins and minerals intake adequacy in hematopoietic stem cell transplant: results of a randomized controlled trial.
Rct Bone marrow transplantation PubMed DOI
C Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain.
Rct Endocrine, metabolic & immune disorders drug targets PubMed DOI
C Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study
Rct Military medicine 1999 PubMed
C Effects of a cream containing madecassoside, 5% panthenol, and copper-zinc-manganese on improving postlaser resurfacing wound healing: A split-face, randomized trial.
Rct Dermatologic therapy PubMed DOI
View all evidence for Manganese →
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Manganese research Best Manganese All Manganese products More from Priority One Nutritional Supplements View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.