🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

3 Veggie Capsule(s) Serving Size
30 Servings
Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 1050mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 200mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 150mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 100mg

Other Ingredients

Rice Flour Cellulose Magnesium Stearate Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (7% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested Use: Take 3 Comfort Guard X24 veggie capsules daily. Best taken with food and 8 fl oz of water.

⚠️ Warnings & Precautions

Do not exceed recommended dose.

This product is not intended for pregnant or nursing mothers or children under the age of 18.

This product is not intended for pregnant or nursing mothers or children under the age of 18.

If you are diabetic, or have a known medical condition, consult your physician prior to taking this or any dietary supplement.

This product was produced in a facility that may also process ingredients containing milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, and soybeans.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Comfort Guard X24 is formulated in the USA in our FDA Registered Facility using natural ingredients.

Helps reduce pain & inflammation

Non GMO

Vegan friendly

Additional Information

Store in a cool, dry place.

Formulated in the USA

90 day money back guarantee

Product Details

DSLD Entry Date 2022-09-22
Product Type Botanical
Form Capsule
Brand KaraMD
DSLD ID 276910
Data Updated 2026-04-11

Research Evidence

311 Research Sources
54 Avg Quality Score
121 Systematic Review
98 Meta Analysis
70 Rct
16 Clinical Trial
2 Other
1 Narrative Review
1 Openfda Safety
A The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis
Meta Analysis Bioscience reports 2021
B Curcumin for depression: a meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2020
B Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2024
B Complementary and Alternative Medicine Therapies for Psoriasis: A Systematic Review
Meta Analysis JAMA dermatology 2018
B Functional foods modulating inflammation and metabolism in chronic diseases: a systematic review
Systematic Review Critical reviews in food science and nutrition 2022
B Effect of curcumin supplementation on symptoms of anxiety: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2024
B The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis
Meta Analysis Complementary therapies in medicine 2021
B Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy on Candida spp.-A Systematic Review
Systematic Review International journal of molecular sciences 2024
B Effects of curcumin on serum inflammatory biomarkers in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis BMC complementary medicine and therapies 2025
B Natural Products in Alzheimer's Disease: A Systematic Review of Clinical Trials and Underlying Molecular Mechanisms
Systematic Review International journal of molecular sciences 2025
View all evidence for Curcumin →

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