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Betaine HCl Plus

product on market Tablet or Pill Douglas Cooper Co. Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for Betaine HCl Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Other Combinations
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
20 mg (2% DV)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Ox Bile extract
100 mg
Papaya, Powder
45 mg
Enzyme Blend
182 mg

Other Ingredients

Cellulose Silica Stearic Acid Magnesium Stearate Croscarmellose Sodium Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 1 tablet with a meal.

Warnings & Precautions

Caution: For adults only.

Consult a physician if pregnant/ nursing, taking medication (especially blood thinners), or have a medical condition (including allergy to papaya, pineapple).

Keep out of reach of children.

Do not eat freshness packets. Keep in bottle.

To report a serious adverse event, or for product information, contact 1-800-234-8686

Formulation Notes

This product is a comprehensive blend of enzymes that support healthy digestion. Formulated with Bromelain, Ox Bile, Pancreatin and Papain, this product helps to optimize the breakdown of fats, carbohydrates and protein.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Breaks down fats, carbs & protein

Contains Sulfites.

Additional Information

Store in a cool, dry place after opening.

Please recycle.

Metadata

Product Details

DSLD Entry Date2022-10-24
Product TypeOther Combinations
FormTablet or Pill
BrandDouglas Cooper Co.
DSLD ID275219
Data Updated2026-04-11
Research

Research Evidence

23
Research Sources
47
Avg Quality
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016 PubMed DOI
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009 PubMed DOI
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017 PubMed DOI
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015 PubMed DOI
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023 PubMed DOI
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019 PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition PubMed DOI
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition PubMed DOI
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009 PubMed DOI
View all evidence for Betaine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.