Betaine HCl Plus

product on market Tablet or Pill Douglas Cooper Co. 🟢 Safety: 100/100
Brand: Douglas Cooper Co.
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
90 Servings
Other Combinations Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

Calcium
20 mg (2% DV)
200 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 200mg
Ox Bile extract
100 mg
Papaya, Powder
45 mg
Enzyme Blend
182 mg

Other Ingredients

Cellulose Silica Stearic Acid Magnesium Stearate Croscarmellose Sodium Pharmaceutical Glaze

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (82% of products) Nutrient (8% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 tablet with a meal.

⚠️ Warnings & Precautions

Caution: For adults only.

Consult a physician if pregnant/ nursing, taking medication (especially blood thinners), or have a medical condition (including allergy to papaya, pineapple).

Keep out of reach of children.

Do not eat freshness packets. Keep in bottle.

To report a serious adverse event, or for product information, contact 1-800-234-8686

🧪 Formulation Notes

This product is a comprehensive blend of enzymes that support healthy digestion. Formulated with Bromelain, Ox Bile, Pancreatin and Papain, this product helps to optimize the breakdown of fats, carbohydrates and protein.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Breaks down fats, carbs & protein

Contains Sulfites.

Additional Information

Store in a cool, dry place after opening.

Please recycle.

Product Details

DSLD Entry Date 2022-10-24
Product Type Other Combinations
Form Tablet or Pill
Brand Douglas Cooper Co.
DSLD ID 275219
Data Updated 2026-04-11

Research Evidence

23 Research Sources
47 Avg Quality Score
18 Rct
3 Systematic Review
1 Meta Analysis
1 Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016
PubMed DOI
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009
PubMed DOI
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017
PubMed DOI
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015
PubMed DOI
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023
PubMed DOI
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019
PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
PubMed DOI
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN
PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
PubMed DOI
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009
PubMed DOI
View all evidence for Betaine →

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