🟡 60/100

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  • Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
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Safety Alerts

⚠️ Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

The safety score is low because the 250mg dose of niacin is more than seven times the recommended daily upper limit of 35mg.

Label Data

1 Tablet(s) Serving Size
100 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

250 mg (1563% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 7.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 250mg UL 35mg

Other Ingredients

Calcium Phosphate Modified Cellulose Stearic Acid Magnesium Stearate Silica

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Sugar Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take one tablet daily, preferably with a meal or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Keep out of the reach of children.

Double safety sealed for your protection. Do not use if either seal is broken or missing.

Caution: Niacin may cause flushing, itching and skin reddening. The effects are temporary and will gradually disappear.

🧪 Formulation Notes

Preservative & gluten free. No sugar, starch, artificial colors, salt, artificial flavors, wheat, yeast, or corn added.

This product is manufactured under strict quality control guidelines; therefore, purity and label potency are guaranteed. Made in USA & American Owned

May help support healthy cholesterol levels.

Additional Information

Store in a cool, dry place.

Lab Tested Potency Assay Guaranteed Release

Questions/Comments Call 1-800-682-9862

Product Details

UPC / SKU 0 79854 10076 1
DSLD Entry Date 2022-11-22
Product Type Vitamin
Form Tablet or Pill
DSLD ID 274693
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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