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Immune Defense Probiotic Great Mixed Berry Flavor

product on market Tablet or Pill Culturelle Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Lactobacillus rhamnosus GG is supported by strong evidence for promoting digestive and immune health. Vitamin C and zinc are well-established micronutrients that contribute to normal immune system function. However, the overall evidence coverage for this specific formulation is very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Immune Defense Probiotic Great Mixed Berry Flavor
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
28
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
90 mg (100% DV)
3 mg (27% DV)
Within RDA (0.3× RDA) 263 studies (A:6, B:134)
Market median: 80.0mg (20 products) 337 studies (A:8, B:183)
Market median: 175.0mg (497 products) 11 studies (A:0, B:1)

Other Ingredients

Xylitol Mannitol Hydroxypropyl Cellulose Stearic Acid Natural Flavors Magnesium Stearate Stevia leaf extract Vegetable Juice
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Once daily

Directions: Take one (1) tablet daily. Tablet may be chewed or swallowed as desired. Continued use is suggested.

Warnings & Precautions

Tamper Evident: Product is sealed within a vial. Do not use if any part of the vial is torn, open or damaged. When first taking Culturelle, you may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms persist after two weeks. For questions, concerns or to report an adverse event, please call (800) 722-3476. www.Culturelle.com

Keep out of reach of children.

Inform a healthcare professional before starting any dietary supplement, particularly if there is a known immune-compromised condition.

Not a reduced calorie food.

Formulation Notes

Culturelle Immune Defense Probiotic leverages a powerful blend containing the #1 clinically studied probiotic, plus Vitamin C, Vitamin C, Zinc, & Elderberry. It helps keep you feeling your best all year long: Zinc Vitamin D Vitamin C Elderberry made with real naturally-sourced elderberry fruit, these chewables taste great. 4-in-1 Immune Support The combination of Lactobacillus rhamnosus GG, Vitamin C, Vitamin D, & Zinc provides 4-in-1 immune support to help keep your immune system strong all year long, both before & after vaccination.

Most clinically researched strain in the world Guaranteed purity & potency

Dairy Gluten Soy Free

Immune defense probiotic with vitamins C & D, Zinc + Elderberry

Helps keep your immune system strong before & after vaccination

Great mixed berry flavor with other natural flavors

Allergy Friendly

While this product contains an ingredient sourced from wheat, it meets the FDA's definition of gluten free (less than 20 ppm gluten).

Additional Information

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight.

Our brand values We’re on a mission to inspire better health & wellness for you & your family. We believe in integrity, so we hold ourselves to the highest standards of truth. We believe in the natural power of your body’s microbiome, & in scientific research & products that will unlock its full potential. We believe in uncompromising quality, safety & proven efficacy. We believe in empowering you to embrace every day with confidence.

#1 Clinically studied probiotic Based on the number of Lactobacillus rhamnosus GG clinical studies, as of January 2021.

Guaranteed potency through date on box when stored as directed.

Metadata

Product Details

UPC / SKU0 49100 40122 5
DSLD Entry Date2022-09-22
Product TypeOther Combinations
FormTablet or Pill
DSLD ID273839
Data Updated2026-04-11
Research

Research Evidence

691
Research Sources
52
Avg Quality
255
Clinical Trial
205
Meta Analysis
123
Rct
81
Systematic Review
18
Cochrane Review
2
Guideline
2
Regulatory Source
1
Other
1
Narrative Review
1
Openfda Safety
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Systematic Review The Cochrane database of systematic reviews 2022 PubMed DOI
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A Probiotics for induction of remission in ulcerative colitis
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A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Probiotics for treating eczema
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Probiotics for treating acute infectious diarrhoea
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022 PubMed DOI
A Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Probiotics to prevent infantile colic
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.