🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

400 IU (100% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 2mg

Other Ingredients

Glucosamine Hydrochloride Cellulose Gel Povidone Stearic Acid Hydroxypropyl Methylcellulose Titanium Dioxide Silicon Dioxide Magnesium Stearate Polyethylene Glycol Sodium Citrate Corn Starch Polysorbate 80 Vitamin D3

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

SUGGESTED USE: Take two tablets daily with a meal. Take for 4-6 weeks to see results.

⚠️ Warnings & Precautions

Contains: Shellfish (Shrimp & Crab).

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

CAUTION: If you are allergic to shellfish, please consult your health care professional before taking this product.

🧪 Formulation Notes

No Artificial Flavors - No Preservatives No Yeast or Gluten

Contains: Shellfish (Shrimp & Crab).

Additional Information

Glucosamine with Vitamin D tablets are made to Nature Made's guaranteed purity and potency standards. - Valid only for U.S. and Puerto Rico residents.

Lot.: Exp.:

2000 mg per two tablets

Helps Maintain Cartilage & Improve Joint Mobility

Enter Code for Wellness Rewards Points at www.Naturemade.com

HELPS MAINTAIN CARTILAGE AND IMPROVE JOINT MOBILITY - Glucosamine, a natural substance of joints, plays a role in the building up of cartilage. Vitamin D helps maintain joint comfort.

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

List No. 1446 L31AA Cat. A448 5A006

Product Details

UPC / SKU 0 31604 01446 9
DSLD Entry Date 2013-10-25
Product Type Other Combinations
Form Tablet or Pill
Brand Nature Made
DSLD ID 27207
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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