🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 29% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Label Data

1 Lozenge(s) Serving Size
33 Servings
Other Combinations Product Type
29% Evidence Coverage

Supplement Facts — Evidence Check

Directline Technology
175 mg
organic Sunflower Lecithin
12.5 mg
Magnolia officinalis
12.5 mg
10 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 10mg
7.5 mg
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 7.5mg
📊 Market median: 340.0mg (243 products) 📚 3 studies — no high-quality reviews
This product: 5mg
2.5 mg
📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)
This product: 2.5mg UL 10mg

Other Ingredients

Colloidal Silicon Dioxide Microcrystalline Cellulose Sucralose Natural Flavors pregelatinized Starch Magnesium Stearate Sodium Starch Glycolate

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (90% of products) Nutrient (61% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

⚠️ Warnings & Precautions

Women who are pregnant or planning a pregnancy should consult their doctor before taking supplements.

Keep out of reach of children.

Do not use if seal is broken.

Additional Information

Sweet dreams are made of ZZZ's.

Store in a cool, dry place.

Product Details

DSLD Entry Date 2022-08-23
Product Type Other Combinations
Form Lozenge
Brand Rebalance
DSLD ID 271799
Data Updated 2026-04-11

Research Evidence

29 Research Sources
48 Avg Quality Score
19 Rct
5 Meta Analysis
3 Systematic Review
2 Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002
View all evidence for Tryptophan →