100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 29% of ingredients have research evidence
B
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
L-Theanine and L-Tryptophan have moderate evidence for promoting relaxation and supporting sleep quality. Magnolia officinalis is also utilized for its calming properties, though broader clinical data is more limited. The overall evidence coverage for this specific ingredient profile is low.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
1 Lozenge(s)
Serving Size
Other Combinations
Product Type
Ingredients
Supplement Facts — Evidence Check
Directline Technology
175 mg
organic Sunflower Lecithin
12.5 mg
Magnolia officinalis
12.5 mg
Market median: 200.0mg (358 products)
9 studies (A:0, B:2)
Market median: 500.0mg (70 products)
Market median: 340.0mg (243 products)
3 studies — no high-quality reviews
Market median: 3.0mg (984 products)
240 studies (A:2, B:109)
Other Ingredients
Colloidal Silicon Dioxide
Microcrystalline Cellulose
Sucralose
Natural Flavors
pregelatinized Starch
Magnesium Stearate
Sodium Starch Glycolate
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Warnings & Precautions
Women who are pregnant or planning a pregnancy should consult their doctor before taking supplements.
Keep out of reach of children.
Do not use if seal is broken.
Additional Information
Sweet dreams are made of ZZZ's.
Store in a cool, dry place.
Metadata
Product Details
DSLD Entry Date2022-08-23
Product TypeOther Combinations
FormLozenge
Data Updated2026-04-11
Research
Research Evidence
B
Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis
Neuroscience and biobehavioral reviews
2021
PubMed
DOI
B
Tryptophan and 5-hydroxytryptophan for depression
Systematic Review
The Cochrane database of systematic reviews
2001
PubMed
B
Tryptophan and 5-hydroxytryptophan for depression
Systematic Review
The Cochrane database of systematic reviews
2002
PubMed
B
The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
B
No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct
European archives of psychiatry and clinical neuroscience
2023
PubMed
DOI
C
The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
C
A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review
Journal of dietary supplements
2021
PubMed
DOI
C
Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
C
Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
C
Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis
The Australian and New Zealand journal of psychiatry
2002
PubMed
View all evidence for Tryptophan →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.