Is 5000 mcg of Biotin safe?

This is 166.7× the recommended daily intake of 0.03 mg. While above typical doses, it may still be within safe limits (UL: None mg).

Coco Skin Plus by John Gilmore, MD

100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
100% of ingredients have research evidence

A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Biotin is commonly used to support keratin infrastructure in the skin, hair, and nails. However, research evidence for its efficacy in healthy individuals is limited. This ingredient profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Open Full PDF View on NIH DSLD →

Details

Label Data

1 Vegetable Liquid Capsule(s)

Serving Size

Servings

Vitamin

Product Type

100%

Evidence Coverage

Ingredients

Supplement Facts — Evidence Check

Biotin

5000 mcg (1667% DV)

166.7× RDA — above typical dose 27 studies (A:0, B:11)

Other Ingredients

Vegetarian Capsule extra virgin Coconut Oil Rice Bran Oil Silicon Dioxide

Claims

Label Claims — Verification

Unverified All Other

Unverified Structure/Function

Info

Product Information

Directions for Use

Directions: Take one (1) liquid veggie capsule daily.

Formulation Notes

CocoSkin Plus supports luxurious hair, soft skin and strong nails. It has just the right balance of biotin and organic coconut oil to effectively give your hair, skin and nails the nutrients they need to grow strong and healthy.

Softer Skin Liquid Veggie Capsules

Metadata

Product Details

UPC / SKU0 638932 868186

DSLD Entry Date2022-06-16

Product TypeVitamin

FormCapsule

BrandJohn Gilmore, MD

DSLD ID267052

Data Updated2026-04-11

Research

Research Evidence

Research Sources

Avg Quality

Meta Analysis

Systematic Review

Rct

Clinical Trial

Regulatory Source

Openfda Safety

B Pentasaccharides for the treatment of deep vein thrombosis

Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI

B Quantitative comparison of the efficacy of clinical drug treatments for primary progressive multiple sclerosis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2023 PubMed DOI

B Dietary interventions for multiple sclerosis-related outcomes

Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI

B Interventions for infantile seborrhoeic dermatitis (including cradle cap)

Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI

B Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis

Meta Analysis Fertility and sterility 2021 PubMed DOI

B Effect of feeding biotin on milk production and hoof health in lactating dairy cows: a quantitative assessment

Meta Analysis Journal of dairy science 2011 PubMed DOI

B Factitious Graves' Disease Due to Biotin Immunoassay Interference-A Case and Review of the Literature

Systematic Review The Journal of clinical endocrinology and metabolism 2016 PubMed DOI

B Effect of biotin on milk performance of dairy cattle: a meta-analysis

Meta Analysis Journal of dairy science 2011 PubMed DOI

B PROVIT: Supplementary Probiotic Treatment and Vitamin B7 in Depression-A Randomized Controlled Trial

Rct Nutrients 2020 PubMed DOI

B High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials

Meta Analysis Multiple sclerosis and related disorders 2021 PubMed DOI

View all evidence for Biotin →

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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.