🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Capsule(s) Serving Size
45 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 60mg
50 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 50mg
Magnolia Bark Extract
24 mg

Other Ingredients

Rice Flour Gelatin Magnesium Stearate Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions For Use: Take two capsules as needed twice per day (multiply ingredients by 2 for total daily serving size).

⚠️ Warnings & Precautions

Caution: Check with your healthcare professional before using this product.

This product is not intended for pregnant or nursing women or those under 18 years of age.

This product is not intended for pregnant or nursing women or those under 18 years of age.

Keep out of reach of children.

Do not combine with antidepressants, prescription sleep aids, tranquilizers or alcohol.

Do not drive or operate machinery after taking.

🧪 Formulation Notes

Supports a sense of well-being Provides nutritional support for relaxation

Additional Information

Store away from excessive heat, light and humidity.

For more information go to advocare.com

Product Details

DSLD Entry Date 2022-05-19
Product Type Other Combinations
Form Capsule
Brand AdvoCare
DSLD ID 265359
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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