Home/ Supplements/ Vitamin B6/ Twilight Time

Twilight Time

product on market Capsule Progressive Professional from Progressive Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines L-Tryptophan, L-Theanine, and Vitamin B6 to support sleep and relaxation, with moderate evidence for these effects. Lemon balm and hops extracts are included for their calming properties, though research coverage for this specific blend is limited. The profile maintains a high safety rating for general use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Twilight Time
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

40 mg (2000% DV)
30.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
500 mg
Market median: 500.0mg (70 products)
Lemon Balm extract
300 mg
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
Hops extract
120 mg
5 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Gelatin Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: One or two capsules one hour before bedtime, or more, as directed by a health care professional.

Warnings & Precautions

Sold only for dispensing by a licensed health professional.

Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.

Keep out of the reach of children.

Warning: If you are pregnant, breastfeeding, or are taking medications such as SSRI's or MAOI's consult your health care professional before using this product.

May cause drowsiness.

Formulation Notes

Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Mood and sleep support

Additional Information

GMP Good Manufacturing Practice Certified GMP Compliant 21 CFR 111

Metadata

Product Details

UPC / SKU3 51821 01017 5
DSLD Entry Date2022-04-11
Product TypeOther Combinations
FormCapsule
DSLD ID263260
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
Compare

Similar Products

View all Vitamin B6 products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.