Home/ Supplements/ Manganese/ Joint, Tendon, Ligament I

Joint, Tendon, Ligament I

product on market Capsule Douglas Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 8% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines MSM and Cynatine FLX, which have moderate evidence for supporting joint comfort and flexibility. L-Arginine and L-Proline provide amino acid precursors for collagen synthesis, while manganese acts as a cofactor for connective tissue enzymes. Overall, the evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Joint, Tendon, Ligament I
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Vegetarian Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
8%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
Cynatine FLX
500 mg
Market median: 1000.0mg (2 products)
400 mg
Market median: 500.0mg (143 products)
L-Proline
250 mg
Glycine
250 mg
ApresFlex
100 mg
Strawberry fruit extract
25 mg
Spinach, Powder
25 mg
15 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
Enzogenol Pine bark extract
10 mg
Market median: 100.0mg (173 products)

Other Ingredients

Hydroxypropylmethylcellulose Stearate Microcrystalline Cellulose Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, adults take 3 capsules daily or as directed by your health professional.

Warnings & Precautions

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Support for joint mobility and ligaments

Additional Information

Store in a cool, dry place.

Gluten-free, Non-GMO

Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Metadata

Product Details

UPC / SKU3 10539 03901 4
DSLD Entry Date2022-04-11
Product TypeOther Combinations
FormCapsule
BrandDouglas Laboratories
DSLD ID261203
Data Updated2026-04-11
Research

Research Evidence

11
Research Sources
47
Avg Quality
7
Rct
2
Meta Analysis
1
Regulatory Source
C Trace elements and Alzheimer dementia in population-based studies: A bibliometric and meta-analysis
Meta Analysis Environmental pollution (Barking, Essex : 1987) 2023 PubMed DOI
C Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone
Rct Journal of animal science 2010 PubMed DOI
C Reducing mineral usage in feedlot diets for Nellore cattle: II. Impacts of calcium, phosphorus, copper, manganese, and zinc contents on intake, performance, and liver and bone status
Rct Journal of animal science 2017 PubMed DOI
C Copper, Ceruloplasmin, Zinc, and Manganese Levels in Brain and Biological Fluids from Parkinson's Disease Patients: Systematic Review and Meta-Analysis
Meta Analysis Cells 2026 PubMed DOI
C Risedronate reverses bone loss in postmenopausal women with low bone mass: results from a multinational, double-blind, placebo-controlled trial. BMD-MN Study Group
Rct The Journal of clinical endocrinology and metabolism 2000 PubMed
C Dietary Reference Intakes: Manganese
Regulatory Source IOM/NAM Dietary Reference Intakes 2000
C Vitamins and minerals intake adequacy in hematopoietic stem cell transplant: results of a randomized controlled trial.
Rct Bone marrow transplantation PubMed DOI
C Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain.
Rct Endocrine, metabolic & immune disorders drug targets PubMed DOI
C Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study
Rct Military medicine 1999 PubMed
C Effects of a cream containing madecassoside, 5% panthenol, and copper-zinc-manganese on improving postlaser resurfacing wound healing: A split-face, randomized trial.
Rct Dermatologic therapy PubMed DOI
View all evidence for Manganese →
Compare

Similar Products

Battery
Combat Nutra · Capsule
100
Cardio Support
Allegany Nutrition · Capsule
100
Joint Synergy +
MRM Nutrition · Capsule
100
Perna Pro With Lemon Flavoring
DaVinci Laboratories · Capsule
100
Aid 4 Joints
Pure Advantage · Capsule
100
View all Manganese products →
Manganese research Best Manganese All Manganese products More from Douglas Laboratories View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.