+Immunity Defend & Resist Complex by Shaklee — Ingredients, Evidence & Safety

Product Label

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Label Data

6 Tablet(s) Serving Size

15 Servings

Botanical with Nutrients Product Type

29% Evidence Coverage

Supplement Facts — Evidence Check

Calories

15 Calorie(s)

Total Carbohydrates

4 Gram(s) (1% DV)

Total Sugars

3 Gram(s)

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Echinacea Extract

168 mg

📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)

This product: 168mg

Larch Tree Extract

300 mg

Defend & Resist Proprietary Blend

480 mg

Other Ingredients

Maltose Microcrystalline Cellulose

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (74% of products) Nutrient (3% of products)

Target Groups

Adult (18 - 50 Years) Kosher Gluten Free

Product Information

📋 Directions for Use

Swallow, chew, or drink as a tea

Directions: Take 6 tablets daily for about 7 days.

⚠️ Warnings & Precautions

Caution: If pregnant or nursing consult your physician prior to use.

Seal under cap for your protection.

Manufactured in a facility that may also process tree nuts, milk, egg, soy, wheat, shellfish, and fish.

🧪 Formulation Notes

Bolsters your immune system Features standardized extracts of echinacea, black elderberry, and larch tree. The immunoactive polysaccharides and polyphenols in these extracts, including anthocyanidins and arabinogalactans, stimulate the body’s natural resistance during seasonal changes. Zinc helps support healthy immune function. Use to supercharge the immune system when you start to feel the need.

Gluten free

Supercharge your immune system

Echinacea, black elderberry, larch tree & zinc

Star-K (Kosher)

No artificial flavors, sweeteners, colors, or preservatives added.

Additional Information

Star-K (Kosher)

Product Details

DSLD Entry Date 2022-02-23

Product Type Botanical with Nutrients

Form Tablet or Pill

Brand Shaklee

DSLD ID 260976

Data Updated 2026-04-11

Research Evidence

38 Research Sources

52 Avg Quality Score

15 Meta Analysis

12 Systematic Review

6 Rct

2 Clinical Trial

1 Regulatory Source

1 Openfda Safety

A Echinacea for preventing and treating the common cold

Meta Analysis The Cochrane database of systematic reviews 2014

PubMed DOI Cochrane

B Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis media in children: Systematic review and meta-analysis

Meta Analysis Clinical nutrition ESPEN 2025

PubMed DOI

B Echinacea for preventing and treating the common cold

Systematic Review The Cochrane database of systematic reviews 2000

PubMed Cochrane

B Echinacea Supplementation Does Not Impact Aerobic Capacity and Erythropoiesis in Athletes: A Meta-Analysis

Meta Analysis Nutrients 2024

PubMed DOI

B Echinacea for preventing and treating the common cold

Meta Analysis The Cochrane database of systematic reviews 2006

PubMed Cochrane

B Therapeutic Potential of a Natural Blend of Aronia melancarpa, Lonicera caerulea, and Echinacea purpurea Extracts in Treating Upper Respiratory Tract Infections: Preliminary Clinical and In Vitro Immunomodulatory Insights

Rct International journal of molecular sciences 2024

PubMed DOI

B Herbal Medicine in Children With Respiratory Tract Infection: Systematic Review and Meta-Analysis

Meta Analysis Academic pediatrics 2018

PubMed DOI

B Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis

Meta Analysis The Lancet. Infectious diseases 2007

PubMed

B Herbal Medicine for Cough: a Systematic Review and Meta-Analysis

Meta Analysis Forschende Komplementarmedizin (2006) 2015

PubMed DOI

B Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and meta-analysis