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D3-K2 with Calcium and Bioperine

product on market Capsule SMNutrition Safety: 90/100
90/100

This product looks safe

  • Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Calcium and Vitamin D3 have strong evidence for supporting bone density and mineral absorption. Vitamin K2 helps direct calcium to the bones, while Bioperine is used to enhance nutrient bioavailability. Overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)

Label

Product Label

Label for D3-K2 with Calcium and Bioperine
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetable Capsule(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
210 mg (16% DV)
125 mcg (625% DV)
Exceeds UL by 1.2× (UL: 0.1 mg) 608 studies (A:16, B:251)
100 mcg
Within RDA (0.8× RDA) 275 studies (A:9, B:175)
Bioperine
5 mg

Other Ingredients

Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement take one (1) vegetable capsule once a day. For best results take 20-30 minutes before a meal with an 8 oz glass of water or as directed by your healthcare professional.

Once-daily capsule

Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Formulation Notes

D3-K2 with Calcium may help support Bone health Immune function Cognition

D3-K2 with Calcium and BioPerine

Bone health complete

Additional Information

Store in a cool, dry place.

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Metadata

Product Details

UPC / SKU8 50005 45847 0
DSLD Entry Date2022-01-22
Product TypeBotanical with Nutrients
FormCapsule
BrandSMNutrition
DSLD ID258933
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.