🟢 89/100

This product is generally safe

  • Folate: 166.7mg is 166.7× the Tolerable Upper Intake Level (1.0mg)
  • Folate: 111mg is 111.0× the Tolerable Upper Intake Level (1.0mg)
  • 86% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 166.7mg is 166.7× the Tolerable Upper Intake Level (1.0mg)
⚠️ Folate: 111mg is 111.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

3 Capsule(s) Serving Size
30 Servings
Botanical with Nutrients Product Type
86% Evidence Coverage

Supplement Facts — Evidence Check

7 mg (412% DV)
📊 5.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 7mg UL 100mg
166.7 mcg DFE (42% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 166.7× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 166.7mg UL 1.0mg
111 mcg DFE (28% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 111.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 111mg UL 1.0mg
300 mg (71% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 300mg
20 mg (182% DV)
✅ 1.8× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 20mg UL 40mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 33.3mg
BioPerine
3.33 mg

Other Ingredients

Hydroxypropyl Methylcellulose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested Use: Take 3 capsules daily for men and 2 capsules daily for women, preferably on an empty stomach, 30-60 minutes prior to bedtime. For best results, avoid taking with foods or supplements containing calcium.

⚠️ Warnings & Precautions

Warning: Do not use if pregnant, nursing, or under the age of 18.

Warning: Do not use if pregnant, nursing, or under the age of 18.

Consult your doctor before using this or any dietary supplement. Immediately discontinue use and contact your doctor if any adverse reactions occur.

Keep out of reach of children.

To report any serious adverse events, please call 800-697-2086 or email info@snac.com.

🧪 Formulation Notes

ZMA-5 combines the original ZMA with the amino acid 5-Hydroxytryptophan (5-HTP) to create a synergistic blend of ingredients. The components in ZMA are co-factors in the conversion of 5-HTP to serotonin, which helps to elevate mood and support sleep. BioPerine has been added to increase the absorption of these nutrients.

ZMA-5 promotes a deep and efficient sleep process and supports muscle recovery from exercise. It also supports a healthy immune system.

Recovery and sleep support formula

Additional Information

The next generation

Servings Per Container: 30 Servings Per Container: 45

Product Details

UPC / SKU 0 94922 14794 3
DSLD Entry Date 2022-01-22
Product Type Botanical with Nutrients
Form Capsule
DSLD ID 258540
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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