Active B-12 + Active Folate
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
A
Label Compliance Grade
Product Label
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Label Data
1 Tablet(s)
Serving Size
60
Servings
Vitamin
Product Type
100%
Evidence Coverage
Supplement Facts — Evidence Check
800 mcg
(200% DV)
✅ 2.0× RDA — within safe limits
📚 225 studies (Tier A: 10, B: 105)
1000 mcg
(16667% DV)
📊 416.7× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
Other Ingredients
Sorbitol
Xylitol
Silica
Magnesium Stearate
natural Cherry flavor
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Dairy Free
Product Information
📋 Directions for Use
Suggested use: take one lozenge daily or as suggested by your healthcare provider. Lozenge may be broken into smaller pieces if lower dosage is desired.
⚠️ Warnings & Precautions
Pregnant or lactating women should contact their healthcare provider prior to using this product.
Do not use if the tamper seal is damaged.
🧪 Formulation Notes
Provides methylation, energy and immune support
Adeno/methyl-cobalamin 1000 mcg - are two most active forms of vitamin b-12 (6S)-5-MTHF Quatrefolic 800 mcg - is the most active form of Folate (Vitamin B-9); non-racemic
Allergen information: Contains no added milk, eggs, soy, wheat, tree nuts, peanuts, fish, shellfish or ingredients from these sources.
Product Details
UPC / SKU
X00172JWOP
DSLD Entry Date
2021-12-18
Product Type
Vitamin
Form
Lozenge
Brand
Core Med Science
DSLD ID
258407
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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