Biotin 5000 mcg by 21st Century — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Capsule(s) Serving Size

Single Vitamin and Mineral Product Type

50% Evidence Coverage

Supplement Facts — Evidence Check

Biotin

5000 mcg (16667% DV)

📊 166.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 5.0mg

Calcium

113 mg (9% DV)

Other Ingredients

Cellulose Gelatin Stearic Acid Contains Less Than 2% of

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (91% of products) Nutrient (57% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a vitamin supplement, adults take one (1) capsule daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

No added Sugar, Yeast, Preservatives, Artificial Flavors or Colors.

Hair, Skin & Nail Support

Gluten free

Biotin is part of the B-complex vitamin family. Biotin 5000 mcg offers additional biotin for those who want higher biotin levels.

Additional Information

Individual results may vary.

Store at room temperature.

Guaranteed quality Laboratory tested

Product Details

UPC / SKU 7 40985 27116 2

DSLD Entry Date 2021-10-22

Product Type Single Vitamin and Mineral

Form Capsule

Brand 21st Century

DSLD ID 258315

Data Updated 2026-04-11

Research Evidence

31 Research Sources

53 Avg Quality Score

12 Meta Analysis

9 Systematic Review

5 Rct

2 Clinical Trial

1 Regulatory Source

1 Openfda Safety

B Pentasaccharides for the treatment of deep vein thrombosis

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

B Quantitative comparison of the efficacy of clinical drug treatments for primary progressive multiple sclerosis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2023

PubMed DOI

B Dietary interventions for multiple sclerosis-related outcomes

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

B Interventions for infantile seborrhoeic dermatitis (including cradle cap)

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

B Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis

Meta Analysis Fertility and sterility 2021

PubMed DOI

B Effect of feeding biotin on milk production and hoof health in lactating dairy cows: a quantitative assessment

Meta Analysis Journal of dairy science 2011

PubMed DOI

B Factitious Graves' Disease Due to Biotin Immunoassay Interference-A Case and Review of the Literature

Systematic Review The Journal of clinical endocrinology and metabolism 2016

PubMed DOI

B Effect of biotin on milk performance of dairy cattle: a meta-analysis

Meta Analysis Journal of dairy science 2011

PubMed DOI

B PROVIT: Supplementary Probiotic Treatment and Vitamin B7 in Depression-A Randomized Controlled Trial