B12 Methylcobalamin 3000 mcg with Folic Acid by Allergy Research Group

87/100

This product is generally safe

Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
67% of ingredients have research evidence

C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin B12 and folate are supported by strong evidence for maintaining neurological function and supporting red blood cell formation. Vitamin C provides antioxidant support and aids in immune health. These ingredients are generally well-tolerated, though the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Open Full PDF View on NIH DSLD →

Details

Label Data

1 Lozenge(s)

Serving Size

Servings

Vitamin

Product Type

67%

Evidence Coverage

Ingredients

Supplement Facts — Evidence Check

Vitamin C

50 mg (56% DV)

Folate

666 mcg DFE (166% DV)

Exceeds UL by 666.0× (UL: 1.0 mg) 226 studies (A:10, B:105)

Vitamin B12

3000 mcg (125000% DV)

1250.0× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Fructose Mannitol Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Silica natural Cherry flavor Raspberry flavor

Claims

Label Claims — Verification

Unverified Nutrient

Unverified All Other

Info

Product Information

Directions for Use

Suggested use As a dietary supplement, adults place 1 lozenge daily under tongue 30 seconds before swallowing, or as directed by a healthcare professional. Do not exceed recommended dose.

Warnings & Precautions

Do not exceed recommended dose.

Formulation Notes

Coenzyme vitamin B12 in the form of methylcobalamin, with folic acid.

Additional Information

Keep in cool, dry place, tightly capped.

Metadata

Product Details

UPC / SKU7 13947 76560 3

DSLD Entry Date2021-10-22

Product TypeVitamin

FormLozenge

BrandAllergy Research Group

DSLD ID257980

Data Updated2026-04-11

Research

Research Evidence

237

Research Sources

Avg Quality

Meta Analysis

Systematic Review

Rct

Clinical Trial

Guideline

Regulatory Source

Openfda Safety

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI

A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency

Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI

A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression

Meta Analysis Nutrients 2021 PubMed DOI

A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis

Systematic Review Irish journal of medical science 2024 PubMed DOI

B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis

Meta Analysis BMJ open gastroenterology 2020 PubMed DOI

B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes

Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI

B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels

Meta Analysis Nutrition reviews 2024 PubMed DOI

B Relationship between vitamin B12 levels and motor development: A systematic review

Systematic Review Clinical nutrition ESPEN 2024 PubMed DOI

B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis

Meta Analysis Frontiers in endocrinology 2023 PubMed DOI

View all evidence for Vitamin B12 →

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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.