N.O.

product on market Capsule Natures Craft Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 29% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

L-arginine and L-citrulline are supported by moderate evidence for increasing nitric oxide levels to support blood flow. Niacin and calcium contribute to cellular energy and metabolic function. Overall, the evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for N.O.
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
29%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
30 mg (2% DV)
30 mg NE (188% DV)
2.1× RDA — within safe limits 196 studies (A:5, B:63)
400 mg
Market median: 500.0mg (143 products)
Market median: 500.0mg (143 products)
Market median: 2000.0mg (275 products)
Market median: 2000.0mg (275 products)
80 mg
Market median: 1500.0mg (104 products) 21 studies (A:0, B:2)

Other Ingredients

Cellulose Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take two (2) capsules twice a day with 8 ounces of water or as directed by your healthcare professional.

Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant or 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Formulation Notes

Max strength Supports energy and focus Boost recovery time Non-stimulating

Additional Information

Store in a cool, dry place.

Formulated in the U.S.A. Sourced from a GMP Certified Facility

Please recycle.

Metadata

Product Details

DSLD Entry Date2021-11-19
Product TypeOther Combinations
FormCapsule
DSLD ID256529
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.