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Calm Cleanse

product on market Capsule SigmaCeutical Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 18% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines oregano leaf extract and caprylic acid, which have moderate evidence for antimicrobial properties. It also includes probiotics and digestive enzymes like protease and cellulase to support gut health. Overall, the clinical evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calm Cleanse
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
18%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Oregano Leaf Extract
500 mg
Caprylic Acid
400 mg
Market median: 80.0mg (20 products) 337 studies (A:8, B:183)
Protease
50 mg
Cellulase
32 mg
Market median: 100.0mg (166 products) 11 studies (A:0, B:1)
Arabinogalactan
50 mg
Anise seed 4:1 extract
50 mg
Black Walnut hulls powder
50 mg
Wormwood leaf powder
50 mg
Market median: 340.0mg (243 products) 3 studies — no high-quality reviews

Other Ingredients

Gelatin Rice powder Vegetable Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 2 capsules daily preferably with meals or as directed by a healthcare professional.

Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, or individuals with a known medical condition should consult a physician prior to taking this or any dietary supplement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Pregnant or nursing mothers, children under the age of 18, or individuals with a known medical condition should consult a physician prior to taking this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Allergen Warning: Contains tree nuts (black walnut).

Formulation Notes

Soothing detox Advanced intestinal support formula

With oregano, probiotics & enzymes

Additional Information

Store in a cool, dry place.

Good Manufacturing Practice Sourced from a GMP Certified Facility Quality Assured Made In USA

Please go to www.sigmaceutical.com for special discounts & offers! SigmaCeutical The sum of all health

Activity level at time of manufacture.

Metadata

Product Details

UPC / SKUX00162NSPV
DSLD Entry Date2021-11-19
Product TypeOther Combinations
FormCapsule
DSLD ID255960
Data Updated2026-04-11
Research

Research Evidence

691
Research Sources
52
Avg Quality
255
Clinical Trial
205
Meta Analysis
123
Rct
81
Systematic Review
18
Cochrane Review
2
Guideline
2
Regulatory Source
1
Other
1
Narrative Review
1
Openfda Safety
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A Probiotics for maintenance of remission in ulcerative colitis
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A Probiotics for induction of remission in ulcerative colitis
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A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Probiotics for treating eczema
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Probiotics for treating acute infectious diarrhoea
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022 PubMed DOI
A Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Probiotics to prevent infantile colic
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.