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Digestive Health Probiotic

product on market Capsule Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Lactobacillus plantarum 299v is researched for its ability to reduce gastrointestinal symptoms and support gut microbiota balance. There is moderate evidence suggesting its efficacy in managing irritable bowel syndrome. However, overall evidence coverage for this specific profile remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Digestive Health Probiotic
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 80.0mg (20 products) 337 studies (A:8, B:183)

Other Ingredients

Potato Starch Hydroxypropyl Methylcellulose Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take one capsule daily with a cold or room temperature drink. Take with food when possible.

Warnings & Precautions

Keep out of reach of children.

For your protection, do not use if tamper evident printed foil seal over capsules is broken.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Formulation Notes

Each capsule is formulated with 10 billion live cells of the Probi Digestis(TM) probiotic strain (Lactobacillus plantarum 299v), which is naturally occurring in humans. It has the ability to survive in the intestinal tract and adhere to the intestinal wall to help promote the growth of good bacteria, Lactobacillus plantarum 299v.

- No Artificial Colors - No Artificial Flavors - No Preservatives - No Yeast - No Gluten

gluten free - dairy free

- 100% vegetarian

Each capsule contains a minimum of 10 billion live cells of Lactobacillus plantarum 299v.

Contains: Soy.

Additional Information

List No: 2760 P300 Cat: A631 1A146

Digestive Health Probiotic capsules are made to Nature Made's guaranteed purity and potency standards.

^Valid only for U.S. and Puerto Rico residents.

No refrigeration necessary.

Made in Canada.

Store in a cool dry place.

^Enter Code for Wellness Rewards Points at www.NatureMade.com 4JMS-HBDA

A high functioning digestive tract is important for overall health and wellness. A healthy digestive tract includes a balanced amount of "beneficial" bacteria, but various factors, including stress and environmental factors, can upset this balance.

NEW

10 BILLION LIVE CELLS POTENCY GUARANTEED THROUGH EXPIRATION DATE

Naturally helps build and maintain a healthy digestive system* Helps promote natural digestive balance*

ONCE DAILY

Metadata

Product Details

UPC / SKU0 31604 02760 5
DSLD Entry Date2013-02-25
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID19067
Data Updated2026-04-11
Research

Research Evidence

691
Research Sources
52
Avg Quality
255
Clinical Trial
205
Meta Analysis
123
Rct
81
Systematic Review
18
Cochrane Review
2
Guideline
2
Regulatory Source
1
Other
1
Narrative Review
1
Openfda Safety
A Probiotics for preventing acute upper respiratory tract infections
Systematic Review The Cochrane database of systematic reviews 2022 PubMed DOI
A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Probiotics for maintenance of remission in ulcerative colitis
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Probiotics for induction of remission in ulcerative colitis
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Probiotics for treating eczema
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Probiotics for treating acute infectious diarrhoea
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022 PubMed DOI
A Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Probiotics to prevent infantile colic
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.