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5-HTP Power

product on market Capsule Nature's Sunshine Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

5-HTP is supported by moderate evidence for supporting mood and sleep, while Vitamin B6 and zinc act as cofactors in neurotransmitter synthesis. Research on the proprietary blend is limited due to a lack of specific dosage data. The overall ingredient profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for 5-HTP Power
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 mg (176% DV)
2.3× RDA — within safe limits 114 studies (A:3, B:35)
3 mg (27% DV)
Within RDA (0.3× RDA) 263 studies (A:6, B:134)
35 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
Proprietary Blend
306 mg

Other Ingredients

Capsule Vegetable Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Use: Take 1 capsule with a meal three times daily.

Warnings & Precautions

Pregnant or lactating women should consult their health care provider prior to taking this supplement. Contact your health care provider if taking any prescription drug.

Do not use this product for more than three months without taking a 2-week rest. Do not use if inner seal is missing or damaged.

Formulation Notes

5-HTP (5-hydroxytryptophan) is a precursor to serotonin. Adaptogenic herbs may enhance its beneficial effects.

Mood support Supports healthy appetite & sleep

Guaranteed pure

Additional Information

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

New look! Same great product

Herbal experts since 1972

Metadata

Product Details

UPC / SKU0 99904 02806 7
DSLD Entry Date2021-08-23
Product TypeBotanical with Nutrients
FormCapsule
DSLD ID255150
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.