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Joint Guard COX-2 Control

product on market Tablet or Pill KAL Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines glucosamine, chondroitin, and MSM, which are researched for supporting joint structure and reducing inflammation. There is moderate evidence that these ingredients may help manage joint discomfort and maintain cartilage integrity. The profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Joint Guard COX-2 Control
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
2 Gram(s) (1% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
MSM
500 mg
Market median: 1000.0mg (2 products)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Devil's Claw
100 mg
Japanese Knotweed root extract
75 mg
Grape skin extract
50 mg
Clove flower bud extract
25 mg

Other Ingredients

Cellulose Stearic Acid Croscarmellose Sodium Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

2 Daily

Directions: Use only as directed. Take 2 tablets daily with ameal or glass of water.

Warnings & Precautions

Warning: Do not use if safety seal is broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product.

Formulation Notes

Patented joint formula with Glucosamine, MSM & Devil's Claw

Discussion: This breakthrough patented COX-2 Control formula features Glucosamine, Chondroitin and MSM for joint comfort.

Additional Information

KAL Innovative Quality Since 1932

Clinical Lifestyles

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 21245 10446 9
DSLD Entry Date2021-09-24
Product TypeOther Combinations
FormTablet or Pill
BrandKAL
DSLD ID254656
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.