Bone Strength Formula With KoAct by Life Extension — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
50% of ingredients have research evidence

A Label Compliance Grade

Product Label

Label for Bone Strength Formula With KoAct

📄 Open Full PDF View on NIH DSLD →

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

4 Capsule(s) Serving Size

30 Servings

Botanical with Nutrients Product Type

50% Evidence Coverage

Supplement Facts — Evidence Check

Calcium

300 mg (30% DV)

Vitamin D

1000 IU (250% DV)

✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Magnesium

100 mg (25% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 100mg

Silica

5 mg

📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)

This product: 5mg

Dried Plum extract

100 mg

Boron

3 mg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 3mg UL 20mg

Other Ingredients

Gelatin Magnesium Stearate Silica

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: Take four (4) capsules daily in divided doses with or without food, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

WARNINGS: - KEEP OUT OF REACH OF CHILDREN.

- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains corn.

- DO NOT EXCEED RECOMMENDED DOSE.

- Do not purchase if outer seal is broken or damaged.

🧪 Formulation Notes

Contains NO no artificial sweeteners, flavors, colors, or preservatives.

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or rice.

Additional Information

01211A Rev. 10/08

Calcium Collagen Chelate

For optimal potency use by: Lot No.:

Read the entire label and follow the directions carefully prior to use.

Product Details

UPC / SKU 7 37870 12111 4

DSLD Entry Date 2011-11-25

Product Type Botanical with Nutrients

Form Capsule

Brand Life Extension

DSLD ID 2504

Data Updated 2026-04-11

Research Evidence

849 Research Sources

56 Avg Quality Score

450 Meta Analysis

152 Rct

137 Systematic Review

73 Clinical Trial

11 Regulatory Source

7 Other

7 Guideline

3 Openfda Safety

2 Cochrane Review

2 Observational

A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)

Meta Analysis The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life

Meta Analysis The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps

Systematic Review The Cochrane database of systematic reviews 2008

PubMed DOI Cochrane

A Calcium and vitamin D for increasing bone mineral density in premenopausal women

Systematic Review The Cochrane database of systematic reviews 2023

PubMed DOI Cochrane

A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019

PubMed DOI

A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021

PubMed DOI

A Calcium channel blockers versus other classes of drugs for hypertension

Systematic Review The Cochrane database of systematic reviews 2021

PubMed DOI

View all evidence for Electrolytes →