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Zestrogen

product on market Capsule Purity Products Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin D, magnesium, and biotin are supported by strong evidence for bone health and metabolic function. The EstroG-100 blend and silica have more limited research regarding their efficacy for hormonal support. Overall, the ingredient profile is considered safe for general use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Zestrogen
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Vegetarian Capsule(s)
Serving Size
30
Servings
Botanical with Nutrients
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

12.5 mcg (63% DV)
Within RDA (0.8× RDA) 608 studies (A:16, B:251)
1500 mcg (5000% DV)
50.0× RDA — above typical dose 27 studies (A:0, B:11)
50 ng (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
EstroG-100 Proprietary Blend
257 mg
15 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)

Other Ingredients

Hypromellose Rice Flour Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take 2 capsules daily. Optimally, for the first 15 days, take two servings daily. For daily use.

Formulation Notes

Soy-free Hormone-free Estrogen-free

Relief from mild hot flashes, night sweats, and other common conditions associated with mesopause Bone, hair, skin & nail support

Additional Information

Intelligent nutritional solutions

Premium grade supplements Since 1993

Metadata

Product Details

DSLD Entry Date2021-02-25
Product TypeBotanical with Nutrients
FormCapsule
DSLD ID244320
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.