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Joint-4

product on market Capsule Xendurance Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines glucosamine, chondroitin, and MSM, which have moderate evidence for supporting joint structure and reducing discomfort. Boswellia serrata extract is included for its researched anti-inflammatory properties. Collectively, these ingredients are widely studied for joint health, though individual efficacy may vary.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Joint-4
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
Market median: 1000.0mg (2 products)

Other Ingredients

Gelatin Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Optimal directions/First 30 days 3 capsules twice a day 3 capsules with morning meal + 3 capsules with evening meal Optimal directions/After 30 days 3 capsules Once a day with meal If joint discomfort increases at lower dosages, increase dosage to 3 capsules-2 times per day.

Warnings & Precautions

Warning: Do not use if pregnant, nursing or under the age of 18.

Warning: Do not use if pregnant, nursing or under the age of 18. Consult with a doctor before taking this or any other dietary supplement, especially if you have or suspect you may have a medical condition, including but not limited to diabetes or hypoglycemia, or are taking any over the counter products.

Use only as directed. Immediately discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if package is open.

Contains: Shellfish

Formulation Notes

Joint Health/Joint Movement

Joint Health/Joint Mobility

Four proven ingredients at research dosages Glucosamine Chondroitin Helps maintain joint health Boswellia MSM Helps respond to inflammation

Guarantee: No added sugar, salt, wheat, yeast or dairy products. No artificial preservatives, colors or flavors.

Made in the USA

Additional Information

Xendurance.com

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU8 55532 00271 4
DSLD Entry Date2021-02-25
Product TypeOther Combinations
FormCapsule
BrandXendurance
DSLD ID243998
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.