5-HTP + Vitamin B6

product on market Softgel Capsule SmarterVitamins 🟢 Safety: 100/100
Brand: SmarterVitamins
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 40% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Softgel(s) Serving Size
30 Servings
Other Combinations Product Type
40% Evidence Coverage

Supplement Facts — Evidence Check

Calories
2 Calorie(s)
Total Fat
0.2 Gram(s) (1% DV)
13.6 mg (799% DV)
📊 10.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 13.6mg UL 100mg
200 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 200mg
200 mg
📊 Market median: 35.0mg (257 products)
Median 35.0mg This product: 200mg

Other Ingredients

Softgel Capsule Beeswax Sunflower Lecithin

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement take 2 liquid softgel daily with a meal, or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Caution: As with any dietary supplement, consult your healthcare practitioner before using this or any other product if you are pregnant, nursing, trying to conceive, taking medication or have a medical condition.

Keep out of reach of children.

🧪 Formulation Notes

5-HTP is an amino acid that your body naturally produces. Your body uses it to produce serotonin, a chemical messenger that sends signals between your nerve cells. Vitamin B-6 is a cofactor in numerous enzymatic reactions. It facilitates the conversion of amino acids from one to another as needed.

Stress Mood Sleep

Made with hemp oil

Additional Information

Cleaner. Better. Smarter.

Store in a cool, dry place away from heat and light.

Product Details

UPC / SKU X002HI1FXP
DSLD Entry Date 2021-02-25
Product Type Other Combinations
Form Softgel Capsule
Brand SmarterVitamins
DSLD ID 243841
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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