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5-HTP + Vitamin B6

product on market Softgel Capsule SmarterVitamins Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 40% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

5-HTP and Vitamin B6 are supported by moderate evidence for their roles in serotonin synthesis and mood regulation. Hemp seed oil provides essential fatty acids, though its specific therapeutic effects in this formulation have limited research coverage. The ingredient profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP + Vitamin B6
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Softgel(s)
Serving Size
30
Servings
Other Combinations
Product Type
40%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
2 Calorie(s)
Total Fat
0.2 Gram(s) (1% DV)
13.6 mg (799% DV)
10.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
200 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
200 mg
Market median: 35.0mg (257 products)

Other Ingredients

Softgel Capsule Beeswax Sunflower Lecithin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement take 2 liquid softgel daily with a meal, or as directed by a healthcare professional.

Warnings & Precautions

Caution: As with any dietary supplement, consult your healthcare practitioner before using this or any other product if you are pregnant, nursing, trying to conceive, taking medication or have a medical condition.

Keep out of reach of children.

Formulation Notes

5-HTP is an amino acid that your body naturally produces. Your body uses it to produce serotonin, a chemical messenger that sends signals between your nerve cells. Vitamin B-6 is a cofactor in numerous enzymatic reactions. It facilitates the conversion of amino acids from one to another as needed.

Stress Mood Sleep

Made with hemp oil

Additional Information

Cleaner. Better. Smarter.

Store in a cool, dry place away from heat and light.

Metadata

Product Details

UPC / SKUX002HI1FXP
DSLD Entry Date2021-02-25
Product TypeOther Combinations
FormSoftgel Capsule
BrandSmarterVitamins
DSLD ID243841
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.