Home/ Supplements/ Glucosamine/ Osteo Bi-Flex One Per Day

Osteo Bi-Flex One Per Day

product on market Tablet or Pill Osteo Bi-Flex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine HCl and Vitamin D are used to support joint health and bone density, respectively. Research provides moderate evidence for the efficacy of glucosamine in managing joint discomfort. The overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo Bi-Flex One Per Day
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Sodium
10 mg (1% DV)
10 mcg (50% DV)
Within RDA (0.7× RDA) 608 studies (A:16, B:251)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)

Other Ingredients

Cellulose Hydroxypropyl Methylcellulose Croscarmellose Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for adult use: Take one (1) tablet per day preferably with food.

1 per day

Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

Contains shellfish (crab, crayfish, lobster, shrimp) ingredients

Keep out of reach of children.

Tamper resistant: Do not use if seal under cap is broken or missing.

Caution: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Formulation Notes

Contains shellfish (crab, crayfish, lobster, shrimp) ingredients.

Free of Gluten Non-GMO

Made in the USA with select ingredients from around the world

Based on two human studies with 5-Loxin Advanced where subjects rated their joint health over time, subjects’ joint health improved within 7 days, and continued to improve throughout the duration of the studies. Based on the results of the Pharmacy Times Survey of Pharmacists’ OTC Recommendations who recommend a “joint health” dietary supplement, 2020-2021.

Osteo Bi-Flex Joint Health Start feeling the difference in your joint comfort in just 7 days with the power of Joint Shield! Helps to: Strengthen Joints Support Flexibility Support Mobility

Joint Shield is our clinically studied beneficial herbal ingredient that has been shown to significantly improve joint comfort in just 7 days. It is a highly concentrated form of Boswellia serrata that helps soothe your joints while improving joint function for comfortable movement.

Supports a Healthy Immune System Shows Improved Joint Comfort within 7 Days!

Glucosamine with Joint Shield

Range of Motion Made to Move During the day, you move your joints in so many different ways, getting up, sitting down, bending and flexing. Osteo Bi-Flex is America’s #1 Joint Health brand and supports joint comfort, so you can enjoy a range of motion for your day’s activities.

Osteo Bi-Flex One Per Day provides you with joint supporting ingredients with the convenience of only one pill per day. This formula includes glucosamine that helps strengthen your joints and supports healthy cartilage. Vitamin D is also included to help maintain healthy bones in adults.

Osteo Bi-Flex is manufactured under the highest standards for product quality, purity and potency.

Additional Information

Store at room temperature and avoid excessive heat.

Source: IRI Total US – Multi Outlet: Latest 52 weeks ending April, 26 2020 See bottom of box for more information about our Ambassador’s Club 20 points Join the Ambassador’s Club for Rewards Visit www.osteobiflex.com for more information.

#1 Pharmacist Recommended Brand

#1 Pharmacist Recommended Brand 2020-2021 Joint health U.S. News & World Report Pharmacy Times

Individual results may vary.

Metadata

Product Details

UPC / SKU0 30768 33043 9
DSLD Entry Date2021-02-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID242714
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
Compare

Similar Products

View all Glucosamine products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.