Migraine Prevention Formula
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 40% of ingredients have research evidence
A
Label Compliance Grade
Product Label
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Label Data
2 Extended Release Tablet(s)
Serving Size
90
Servings
Other Combinations
Product Type
40%
Evidence Coverage
Supplement Facts — Evidence Check
400 mg
(23500% DV)
📊 307.7× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
360 mg
(90% DV)
📊 Market median: 4002.0mg (1 products)
📚 20 studies (Tier A: 0, B: 2)
Butterbur
150 mg
100 mg
📊 Market median: 380.0mg (120 products)
📚 8 studies — no high-quality reviews
Organic Whole Food Blend
75 mg
Other Ingredients
Cellulose
Hydroxypropyl Methycellulose
Stearic Acid
Magnesium Stearate
Silica
Pharmaceutical Glaze
Label Claims — Verification
❓
All Other
All Other (99% of products)
Structure/Function (85% of products)
Nutrient (48% of products)
No Claim (1% of products)
Target Groups
Vegetarian
Adult (18 - 50 Years)
Gluten Free
Product Information
🧪 Formulation Notes
Soothing brain support
With standardized butterbur and feverfew, riboflavin and magnesium in an organic, whole food blend
PA free
Vegetarian
Gluten free
Manufactured in an independently certified GMP facility
Additional Information
Formulated by doctors, recommended by medical professionals
Product Details
DSLD Entry Date
2020-11-21
Product Type
Other Combinations
Form
Tablet or Pill
Brand
Dr. Knowles
DSLD ID
240210
Data Updated
2026-04-11
Research Evidence
22
Research Sources
49
Avg Quality Score
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B
Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
B
Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
B
Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
B
Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
C
Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
C
The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
C
Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
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