Trifolamin
80/100
This product is generally safe
- Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
- 100% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Lozenge(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Supplement Facts — Evidence Check
680 mcg DFE
(170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
3000 mcg
(125000% DV)
📊 1250.0× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
Other Ingredients
Mannitol
Modified Cellulose
natural Orange flavor
natural Orange color
Vegetable Stearate
Citric Acid
Luo Han Guo
Label Claims — Verification
❓
Nutrient
❓
All Other
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Recommended Use: As a dietary supplement, take one lozenge per day, or as directed by your health care practitioner. Allow lozenge to dissolve slowly and completely in mouth and swallow.
⚠️ Warnings & Precautions
Report any adverse reactions to 860-623-6314
For professional use only
Keep out of reach of children.
🧪 Formulation Notes
Three forms of Vitamin B12 + Folate
Manufactured in a GMP Registered Facility in the USA
Made with GMO-free ingredients
Notice: Color, size or shape may appear different between lots.
Does not contain gluten.
Additional Information
Store at room temperature.
Guaranteed GMP Compliant Products
Product Details
UPC / SKU
8 79452 00454 2
DSLD Entry Date
2020-11-21
Product Type
Vitamin
Form
Lozenge
Brand
Designs for Health
DSLD ID
239500
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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