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Niacin 400 mg

product on market Tablet or Pill Viva Vitamins Safety: 60/100
60/100

Review before taking

  • Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol management and metabolic function, with strong evidence for its role in lipid regulation. However, the safety score indicates potential concerns, such as the risk of flushing or liver enzyme elevations. Clinical evidence for general supplementation is well-established but requires caution regarding dosage.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Niacin is more than 11 times the recommended upper limit for daily intake.

Label

Product Label

Label for Niacin 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
100
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg (2000% DV)
Exceeds UL by 11.4× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Croscarmellose Sodium
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, adults take one tablet daily with meals, or as directed by a health care professional.

Warnings & Precautions

Keep out of reach of children.

Do not use if safety seal under cap is broken or missing.

Formulation Notes

Derived from Inositol hexanicotinate (a compound of niacin and the B vitamin inositol),this product will provide the cholesterol supporting benefits of niacin without the undesirable flushing effects or the gastrointestinal discomfort often associated with niacin supplementation.

Non-flushing Niacin

Contains No: Gluten, sugar, salt, yeast, corn, wheat, dairy, citrus, egg, fish products, artificial coloring, flavoring, or preservatives.

Made in the USA

Non-GMO

Manufactured in an NSF - GMP Certified facility

Additional Information

Store in a cool, dry place and away from direct light.

We always use the highest quality ingredients Premium formulas

In God we trust

Metadata

Product Details

UPC / SKU7 26899 24474 4
DSLD Entry Date2020-09-25
Product TypeVitamin
FormTablet or Pill
BrandViva Vitamins
DSLD ID237010
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.