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  • Niacin: 430mg is 12.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
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Safety Alerts

⚠️ Niacin: 430mg is 12.3× the Tolerable Upper Intake Level (35mg)

This supplement contains a dose of niacin that is more than 12 times the recommended maximum daily limit.

Label Data

1 Capsule(s) Serving Size
75 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

430 mg (2688% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 12.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 430mg UL 35mg

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose L-Leucine

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested use As a dietary supplement, 1 capsule two or three times daily with meals, or as directed by a healthcare practitioner.

⚠️ Warnings & Precautions

Do not take large amounts of Niacin (greater than 1.5 grams per day) without first consulting a healthcare practitioner.

🧪 Formulation Notes

Provides inositol hexanicotinate. Taken orally, the niacin releases slowly, thereby minimizing the likelihood of "niacin flush". Though chemically linked to inositol, the niacin in this formulation is highly bio-available.

Inositol Hexanicotinate

Hypoallergenic

Additional Information

Keep in a cool, dry place, tightly capped.

Product Details

UPC / SKU 7 13947 70370 4
DSLD Entry Date 2020-08-23
Product Type Vitamin
Form Capsule
DSLD ID 233222
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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