Methyl B12 Plus
80/100
This product is generally safe
- Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
- 100% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Lozenge(s)
Serving Size
90
Servings
Vitamin
Product Type
100%
Evidence Coverage
Supplement Facts — Evidence Check
667 mcg DFE
(167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
1000 mcg
(41667% DV)
📊 416.7× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
Other Ingredients
Xylitol
Mannitol
natural Cherry flavor
natural Berry flavor
natural Vanilla flavor
Croscarmellose Sodium
Hydroxypropyl Cellulose
Ascorbyl Palmitate
Malic Acid
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Suggested Use: As a dietary supplement, adults take 1 lozenge daily or as directed by your healthcare professional. Allow lozenge to dissolve in mouth and then swallow.
⚠️ Warnings & Precautions
Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your healthcare professional before using this product.
Keep out of the reach of children.
Use only if safety seal is intact.
🧪 Formulation Notes
Gluten-free, Non-GMO
Great-tasting dissolvable tablet with Metafolin
Additional Information
Store in a cool, dry place.
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our manufacturing excellence
Product Details
UPC / SKU
3 10539 97770 5
DSLD Entry Date
2020-08-23
Product Type
Vitamin
Form
Lozenge
Brand
Douglas Laboratories
DSLD ID
232190
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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