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Calcium Microcrystalline Hydroxyapatite

product on market Tablet or Pill Douglas Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 25% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Microcrystalline hydroxyapatite provides calcium and phosphorus, which are essential for bone mineralization and structural integrity. Boron supports bone health by influencing calcium metabolism, though evidence for its specific efficacy in supplements is limited. Research generally supports the use of these minerals for maintaining skeletal density.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calcium Microcrystalline Hydroxyapatite
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
125
Servings
Mineral
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
500 mg (38% DV)
260 mg (21% DV)
Within RDA (0.4× RDA) 13 studies (A:0, B:3)
Microcrystalline Hydroxyapatite
2000 mg
5 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Cellulose Croscarmellose Sodium Coating Stearic Acid Vegetable Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 2 tablets daily or as directed by your health professional.

Warnings & Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Gluten-free, Non-GMO

Healthy bones and teeth

Additional Information

Store in a cool, dry place.

Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Metadata

Product Details

UPC / SKU3 10539 01776 0
DSLD Entry Date2020-08-23
Product TypeMineral
FormTablet or Pill
DSLD ID232075
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.