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Sublingual Pure NAD+

product on market Tablet or Pill Alive By Nature Safety: 80/100
80/100

This product is generally safe

  • Nicotinamide Adenine Dinucleotide: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Nicotinamide Adenine Dinucleotide (NAD+) and TMG are researched for their roles in cellular energy metabolism and methylation support. Evidence for the efficacy of sublingual NAD+ supplementation remains limited. These ingredients generally maintain a favorable safety profile for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide Adenine Dinucleotide: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Sublingual Pure NAD+
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
240
Servings
Non-Nutrient/Non-Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 3.6× (UL: 35 mg) 196 studies (A:5, B:63)
TMG
25 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews

Other Ingredients

Mannitol Crospovidone Citrus Burst Monk Fruit extract Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use For best results, take one (1) tablet, 2-4 times per day. Place tablet under the tongue to dissolve. May be taken with or without meals.

Warnings & Precautions

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical conditions should consult a physician before using.

Do not use if safety seal is broken or missing.

Formulation Notes

Supports: Cognition Neurogenesis Memory Metabolism

Nicotinamide Adenine Dinucleotide

No artificial colors, preservatives or additives. Gluten-free. Non-GMO.

Suitable for vegans.

Made in the USA Made in a FDA Registered Facility GMP Good Manufacturing Practice Certified

Additional Information

Store tightly in a cool, dry place.

Made in the USA Made in a FDA Registered Facility GMP Good Manufacturing Practice Certified

Metadata

Product Details

UPC / SKU6 56165 99701 5
DSLD Entry Date2020-07-23
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
DSLD ID230852
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.