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E-400 IU with Selenium 50 mcg

product on market Softgel Capsule Esmond Natural Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin E and selenium act as antioxidants that help protect cells from oxidative stress. There is moderate research evidence supporting their role in maintaining immune function and cellular health. These ingredients are generally well-tolerated when taken within recommended daily allowances.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for E-400 IU with Selenium 50 mcg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Single Vitamin and Mineral
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 IU (1333% DV)
17.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
50 mcg (71% DV)
Within RDA (0.9× RDA) 173 studies (A:0, B:67)

Other Ingredients

Gelatin Vegetable oil Vegetable Glycerin yellow Beeswax Soy Lecithin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) softgel daily, preferably with a meal.

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

Vitamin E and selenium are two powerful antioxidants that fight free radicals. Studies have shown that oxidative stress caused by free radicals may contribute to the premature aging of cells. Vitamin E and selenium also promote immune function, while vitamin E helps support cardiovascular health. This product delivers 400 IU of vitamin E and 50 mcg of selenium.

Additional Information

GMP Good Manufacturing Process Natural Products Association Certified

50 softgels Esmondnatural Integrated health

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU06 41399 08774 8
DSLD Entry Date2020-07-23
Product TypeSingle Vitamin and Mineral
FormSoftgel Capsule
DSLD ID230733
Data Updated2026-04-11
Research

Research Evidence

273
Research Sources
55
Avg Quality
131
Meta Analysis
61
Systematic Review
55
Rct
19
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Other
1
Observational
1
Openfda Safety
A Selenium for preventing cancer
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Selenium supplementation for the primary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Selenium supplementation for critically ill adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
B Selenium and prostate cancer: systematic review and meta-analysis
Meta Analysis The American journal of clinical nutrition 2012 PubMed DOI
B Selenium supplementation for Hashimoto's thyroiditis
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Selenium, antioxidants, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis The American journal of clinical nutrition 2020 PubMed DOI
B The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2017 PubMed DOI
B Meta-analysis of selenium effects on the meat quality of broilers
Meta Analysis Poultry science 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.