Milk Thistle 525 mg by Natrol — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Capsule(s) Serving Size

30 Servings

Botanical Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Milk Thistle extract

525 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 525mg

Dandelion

85 mg

📊 Market median: 300.0mg (159 products)

Median 300.0mg This product: 85mg

Black Radish

60 mg

Burdock

60 mg

📊 Market median: 425.0mg (88 products)

Median 425.0mg This product: 60mg

Ginger Rhizome Extract

60 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 60mg

Parsley

35 mg

Other Ingredients

Hypromellose Maltodextrin Magnesium Stearate Silicon Dioxide

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: Take 2 capsules, one time daily, with a meal.

⚠️ Warnings & Precautions

Warning: Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Keep out of reach of children.

🧪 Formulation Notes

Herbal blend for liver and digestive detoxification while supporting liver health 420mg Silymarin per serving

Supports elimination of metabolic by-products Provides antioxidant protection

No: Milk, Egg, Fish, Crustacean Shellfish, Tree Nuts, Peanuts, Wheat, Soybeans, Yeast, Artificial Colors or Flavors, Added Sugar or Preservatives

Digestive health

Milk Thistle extract Milk Thistle 525mg per serving

Vegetarian

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 0 47469 05238 6

DSLD Entry Date 2020-07-23

Product Type Botanical

Form Capsule

Brand Natrol

DSLD ID 230610

Data Updated 2026-04-11

Research Evidence

69 Research Sources

55 Avg Quality Score

34 Meta Analysis

26 Systematic Review

5 Rct

3 Clinical Trial

1 Openfda Safety

A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis

Meta Analysis Japan journal of nursing science : JJNS 2024

PubMed DOI

B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications

Meta Analysis Asia Pacific journal of clinical nutrition 2025

PubMed DOI

B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

Meta Analysis The Cochrane database of systematic reviews 2007

PubMed

B Pharmacotherapy for trichotillomania

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review

Meta Analysis Medicine 2024

PubMed DOI

B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Meta Analysis BMC complementary medicine and therapies 2025

PubMed DOI

B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

Meta Analysis Medicine 2020

PubMed DOI

B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis

Meta Analysis Annals of hepatology 2024

PubMed DOI

View all evidence for Milk Thistle →