DIM 250 mg by HMS Nutrition — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Capsule(s) Serving Size

60 Servings

Other Combinations Product Type

50% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin E

50 mg (333% DV)

📊 3.3× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 50mg UL 1000mg

Copper

0.1 mg (6% DV)

✅ Within RDA (0.1× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.1mg UL 10mg

Manganese

0.1 mg (2% DV)

📊 Market median: 10.0mg (102 products) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 0.1mg UL 11mg

Diindolylmethane

250 mg

📊 Market median: 200.0mg (3 products) 📚 10 studies (Tier A: 1, B: 3)

This product: 250mg

Dong Quai 4:1 extract

200 mg

Black Pepper extract

6 mg

Other Ingredients

Vegetable Cellulose Capsule Rice Flour

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (98% of products) Structure/Function (81% of products) Nutrient (56% of products) Qualified Health (2% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested use: Take 2 capsules daily with water, or as directed by a healthcare practitioner.

⚠️ Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant and nursing mothers, children under the age of 18, and individuals with a known medical condition or who are taking prescription medication should consult a physician before taking this or any dietary supplement.

🧪 Formulation Notes

Manufactured at an FDA registered facility

250 mg pure diindolylmethane Antioxidant Vitamin E Black pepper extract for enhanced absorption

Additional Information

Made in the USA GMP Good manufacturing practice Consistent Quality

Product Details

UPC / SKU X001NNJ98X

DSLD Entry Date 2020-07-23

Product Type Other Combinations

Form Capsule

Brand HMS Nutrition

DSLD ID 229885

Data Updated 2026-04-11

Research Evidence

253 Research Sources

55 Avg Quality Score

128 Meta Analysis

52 Systematic Review

41 Rct

24 Clinical Trial

3 Regulatory Source

1 Narrative Review

1 Other

1 Guideline

1 Openfda Safety

A Vitamin E supplementation in pregnancy

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Systematic Review The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin E for Alzheimer's disease and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2008

PubMed DOI Cochrane

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

A Exercise for intermittent claudication

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis

Meta Analysis Nutritional neuroscience 2021

PubMed DOI

A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis

Meta Analysis European journal of clinical nutrition 2023

PubMed DOI

A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

Rct JAMA 2011

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.

Guideline JAMA 2022

PubMed DOI

View all evidence for Vitamin E →