🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

Thiamine, magnesium, and zinc are supported by moderate evidence for supporting neurological function and stress response. However, the overall evidence coverage for this specific formulation is limited. The product maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

5 mg (417% DV)
📊 4.2× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 5mg
40 mg (10% DV)
✅ Within RDA (0.1× RDA of 420 mg) 📚 316 studies (Tier A: 8, B: 159)
RDA 420mg This product: 40mg UL 350mg
1 mg (9% DV)
✅ Within RDA (0.1× RDA of 11 mg) 📚 263 studies (Tier A: 6, B: 134)
RDA 11mg This product: 1mg UL 40mg
Proprietary Blend
75 mg

Other Ingredients

Cellulose Capsule Vegetable Magnesium Stearate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommended use: Take 1 capsule daily as needed.

⚠️ Warnings & Precautions

Do not use if inner seal is missing or damaged.

🧪 Formulation Notes

Increase your confidence. Support a healthy mood. Reduce fatigue.

AnxiousLess features Sceletium tortuosum plus I-theanine, magnesium, thiamin and zinc to give you non-drowsy relief.

Situational stress relief Relieves occasional anxiousness Increases calm and confidence

Additional Information

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

New look! Same great product

Guaranteed Pure

Herbal experts since 1972

Product Details

UPC / SKU 0 99904 01167 0
DSLD Entry Date 2020-05-22
Product Type Other Combinations
Form Capsule
DSLD ID 220789
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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