Home/ Supplements/ Glucosamine/ Glucosamine & Chondroitin 500 mg / 400 m...

Glucosamine & Chondroitin 500 mg / 400 mg

product on market Capsule Natural Factors Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine and chondroitin sulfate are commonly used to support joint health and manage osteoarthritis symptoms. Clinical evidence for their efficacy is generally considered moderate to limited, with varying results across studies. These ingredients work by supporting the structural integrity of cartilage within the joints.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine & Chondroitin 500 mg / 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
40
Servings
Non-Nutrient/Non-Botanical
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Sodium
90 mg (4% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Gelatin capsule Magnesium Stearate Microcrystalline Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: 3 capsules per day with or without meals or as directed by a health professional.

Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Contains shellfish (shrimp, crab).

Formulation Notes

Glucosamine and Chondroitin provide key building blocks to support healthy cartilage and other connective tissue, and have a beneficial relationship to support healthy joint function.

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, tree nuts, or GMOs.

Helps maintain structural integrity of joints & connective tissue

Additional Information

isura Non-GMO - Mass Spec Documentation Lab tested

For freshness, store in a cool, dry place

Product of Canada Recyclable container and label.

Purity & Potency Guaranteed

Metadata

Product Details

UPC / SKU0 68958 02687 9
DSLD Entry Date2020-05-22
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID220597
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
Compare

Similar Products

View all Glucosamine products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.