🟡 60/100

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  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
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Safety Alerts

⚠️ Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

This product has a low safety score because the amount of niacin in a single dose is significantly higher than the recommended maximum daily limit.

Label Data

1 Tablet(s) Serving Size
500 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

500 mg (3125% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg

Other Ingredients

Stearic Acid Microcrystalline Cellulose Carnauba wax Hydroxypropylcellulose Magnesium Stearate Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Directions: Adults take one tablet daily at mealtime. Consult your physician before exceeding recommended use.

⚠️ Warnings & Precautions

Warning: Do not take if you are pregnant or lactating.

Do not take if you have low blood pressure without first consulting your physician.

If flushing or itching occurs, drinking 1 or 2 glasses of water may alleviate symptoms.

Niacin may cause flushing or itching, but Niacin-Time is prepared to minimize or eliminate these side effects by providing a gradual release of Niacin over a period of several hours. Please be aware that a flush may occur. Taking this product with warm fluids may enhance this effect.

🧪 Formulation Notes

Timed-Release Niacin 500 mg

Energy production Heart health Nerve function

Gluten-free No artificial preservatives

Niacin (vitamin B-3) is an essential B vitamin that's important for properly metabolizing fat and fat-like substances, such as cholesterol.

Niacin supports energy production, and healthy cardiovascular and nervous system function.

Potency & quality guaranteed An FDA regulated facility

Additional Information

Keep bottle tightly closed. Store away from heat and moisture.

Product Details

UPC / SKU 0 88395 02795 6
DSLD Entry Date 2020-03-24
Product Type Vitamin
Form Tablet or Pill
Brand Carlson
DSLD ID 216174
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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