🟡 60/100

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  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
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Safety Alerts

⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

The safety score is low because the 100mg dose of niacin is nearly three times higher than the recommended maximum daily limit of 35mg.

Label Data

1 Tablet(s) Serving Size
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

100 mg (625% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Croscarmellose Sodium Vegetable Stearin Magnesium Stearate Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Directions: Adults: Take one tablet daily at mealtime.

⚠️ Warnings & Precautions

Warning: Do not take if you are pregnant or lactating.

Do not take if you have low blood pressure without first consulting your physician.

Note: Niacin may cause a warm flushing of the skin which may last minutes or hours and can often be relieved by drinking 1 or 2 glasses of water.

🧪 Formulation Notes

Cholesterol metabolism Heart health Nerve function

Niacin (vitamin B-3) is an essential B vitamin that's important for properly metabolizing fat and fat-like substances, such as cholesterol.

Niacin supports healthy cardiovascular and nervous system function.

Gluten-free Yeast-free

Vegetarian

Potency & quality guaranteed An FDA regulated facility

Product Details

UPC / SKU 0 88395 02773 4
DSLD Entry Date 2020-03-24
Product Type Vitamin
Form Tablet or Pill
Brand Carlson
DSLD ID 216163
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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